Functional defects in the fanconi anemia pathway in pancreatic cancer cells. - sprookjes - yvandenbroek - TriplyDB

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

http://www.wikidata.org/entity/Q35102998

about

Susceptibility pathways in Fanconi's anemia and breast cancer Genomic alterations in pancreatic cancer and their relevance to therapy Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies The Fanconi anemia pathway and ubiquitin Pancreatic cancer.The ubiquitin system, disease, and drug discovery.Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells.Taking a Bad Turn: Compromised DNA Damage Response in Leukemia Pancreatic ductal adenocarcinoma: risk factors, screening, and early detection.HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells.Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.Molecular characteristics of pancreatic ductal adenocarcinoma Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Drug therapy for hereditary cancers Formation of cyclophosphamide specific DNA adducts in hematological diseases DNA repair mechanisms in cancer development and therapy Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.Fanconi anaemia genes and susceptibility to cancer.Amplification of EMSY gene in a subset of sporadic pancreatic adenocarcinomas Molecular genetics of pancreatic intraepithelial neoplasia.The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.The Fanconi anaemia/BRCA pathway and cancer susceptibility. Searching for new therapeutic targets.Morphogenesis of pancreatic cancer: role of pancreatic intraepithelial neoplasia (PanINs)Emerging molecular biology of pancreatic cancer.Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine Familial pancreatic cancer: from genes to improved patient care.Immortalizing the complexity of cancer metastasis: genetic features of lethal metastatic pancreatic cancer obtained from rapid autopsy.Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes.Chemotherapy and signaling: How can targeted therapies supercharge cytotoxic agents?Somatic variation and cancer: therapies lost in the mix.The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes.Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis.RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells.Curcumin reverses cisplatin resistance in cisplatin-resistant lung caner cells by inhibiting FA/BRCA pathway.Genome annotation by shotgun inactivation of a native gene in hemizygous cells: application to BRCA2 with implication of hypomorphic variants.Inhibitory effects of marine-derived DNA-binding anti-tumour tetrahydroisoquinolines on the Fanconi anaemia pathway.Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors.Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange.

P2860

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P2860

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

http://www.wikidata.org/entity/Q35102998

description

2004 nî lūn-bûn

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2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2004 թվականի օգոստոսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

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Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

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type

label

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

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Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

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prefLabel

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

@ast

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

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S0002-9440(10)63329-9

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The American Journal of Pathology

P1476

Functional defects in the fanconi anemia pathway in pancreatic cancer cells.

@en

P2093

David A Dezentje

http://www.w3.org/2001/XMLSchema#string

Dong Shen

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Eike Gallmeier

http://www.w3.org/2001/XMLSchema#string

Jonathan R Brody

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Michiel S van der Heijden

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Scott E Kern

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Steven C Cunningham

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P2860

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity

Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors

The Fanconi anaemia/BRCA pathway

A novel ubiquitin ligase is deficient in Fanconi anemia

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

Biallelic inactivation of BRCA2 in Fanconi anemia

BRCA2 is required for homology-directed repair of chromosomal breaks

Functional activity of the fanconi anemia protein FAA requires FAC binding and nuclear localization.

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2

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15277238

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1618568

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