Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.
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The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetasesSynthetic Biology in Action: Developing a Drug Against MDR-TBStructure and Stereospecificity of the Dehydratase Domain from the Terminal Module of the Rifamycin Polyketide SynthaseThe TetR family of transcriptional repressors.Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticusEctopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapesA multiplasmid approach to preparing large libraries of polyketides.Artificial chromosomes for antibiotic-producing actinomycetes.Sponge Microbiota Are a Reservoir of Functional Antibiotic Resistance Genes.Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes.Combinatorial biosynthesis--potential and problems.Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42.Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1.Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release mechanism from nonribosomal peptide synthetases.Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.Genetic localization and molecular characterization of the nonS gene required for macrotetrolide biosynthesis in Streptomyces griseus DSM40695.Identification and in vivo functional analysis of a virginiamycin S resistance gene (varS) from Streptomyces virginiae.Role of crotonyl coenzyme A reductase in determining the ratio of polyketides monensin A and monensin B produced by Streptomyces cinnamonensisIdentification of the varR gene as a transcriptional regulator of virginiamycin S resistance in Streptomyces virginiaeMeaA, a putative coenzyme B12-dependent mutase, provides methylmalonyl coenzyme A for monensin biosynthesis in Streptomyces cinnamonensis.Microbial origin of plant-type 2-keto-3-deoxy-D-arabino-heptulosonate 7-phosphate synthases, exemplified by the chorismate- and tryptophan-regulated enzyme from Xanthomonas campestris.Biosynthesis of polyketides in heterologous hostsBiosynthetic gene cluster of simocyclinone, a natural multihybrid antibioticTools for metabolic engineering in StreptomycesAminobenzoates as building blocks for natural product assembly lines.Biosynthesis of 3,5-AHBA-derived natural products.Evolutionary divergence of sedoheptulose 7-phosphate cyclases leads to several distinct cyclic products.Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.Regulatory role of tetR gene in a novel gene cluster of Acidovorax avenae subsp. avenae RS-1 under oxidative stressDraft Genome Sequence of the Rifamycin Producer Amycolatopsis rifamycinica DSM 46095.The pharmacogenetics of NAT: structural aspects.How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strainsRecent developments in the production of novel polyketides by combinatorial biosynthesis.A comparative analysis of the sugar phosphate cyclase superfamily involved in primary and secondary metabolismThe 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively.
P2860
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P2860
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@ast
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@en
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@nl
type
label
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@ast
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@en
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@nl
prefLabel
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@ast
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@en
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@nl
P2093
P1476
Biosynthesis of the ansamycin ...... ycolatopsis mediterranei S699.
@en
P2093
Hoffmann D
Hutchinson CR
P356
10.1016/S1074-5521(98)90141-7
P577
1998-02-01T00:00:00Z