The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737
about
Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization toolBIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cellsCell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenograftsDown-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-κB mediated activation of MMP-9Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo.The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.Development of a capillary electrophoresis platform for identifying inhibitors of protein-protein interactionsTargeting mcl-1 for radiosensitization of pancreatic cancers.Combining paclitaxel with ABT-263 has a synergistic effect on paclitaxel resistant prostate cancer cells.miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer.A direct regulatory interaction between chaperonin TRiC and stress-responsive transcription factor HSF1.Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo.TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo.Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes.Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survivalHeat Shock Factor 1 Depletion Sensitizes A172 Glioblastoma Cells to Temozolomide via Suppression of Cancer Stem Cell-Like PropertiesKnockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.BAG3 protects against hyperthermic stress by modulating NF-κB and ERK activities in human retinoblastoma cells.The Evaluation of WBP2NL-Related Genes Expression in Breast Cancer.Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation.A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers.Norcantharidin combined with ABT-737 for hepatocellular carcinoma: Therapeutic effects and molecular mechanisms.Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma.Aggravation of diabetic nephropathy in BCL-2 interacting cell death suppressor (BIS)-haploinsufficient mice together with impaired induction of superoxide dismutase (SOD) activity.BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.miR-217-5p induces apoptosis by directly targeting PRKCI, BAG3, ITGAV and MAPK1 in colorectal cancer cells.BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells.Clitocine potentiates TRAIL-mediated apoptosis in human colon cancer cells by promoting Mcl-1 degradation.The role of heat shock proteins and co-chaperones in heart failure.
P2860
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P2860
The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@ast
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@en
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@nl
type
label
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@ast
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@en
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@nl
prefLabel
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@ast
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@en
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@nl
P2093
P2860
P356
P1476
The stress protein BAG3 stabil ...... sistance to antagonist ABT-737
@en
P2093
Cristina Daniel
Lawrence J Marnett
Mariana Boiani
Michael D Hogarty
Xueyuan Liu
P2860
P304
P356
10.1074/JBC.M112.414177
P407
P577
2013-01-22T00:00:00Z