Positive and negative regulation of T-cell activation by adaptor proteins. - sprookjes - yvandenbroek - TriplyDB

Positive and negative regulation of T-cell activation by adaptor proteins.

Positive and negative regulation of T-cell activation by adaptor proteins.

http://www.wikidata.org/entity/Q34572179

about

Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif HIP-55 is important for T-cell proliferation, cytokine production, and immune responses Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation Increased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domains GRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-γ1 Activation and Cytokine Production.Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells Approaches to define antigen receptor-induced serine kinase signal transduction pathways.Regulation of T cell development and activation by creatine kinase B.ADAP-ting TCR signaling to integrins.CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76?Genetic analysis of integrin activation in T lymphocytes.Thymic selection revisited: how essential is it?Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation.All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton.Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor.The TCR ADAPts to integrin-mediated cell adhesion.GTPases and T cell activation.Negative feedback of T cell activation through inhibitory adapters and costimulatory receptors.Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury.Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases.Protein kinase C and beyond.TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response.Signaling pathways in Th2 development.A function for tyrosine phosphorylation of type 1 inositol 1,4,5-trisphosphate receptor in lymphocyte activation T cell receptor ligation induces the formation of dynamically regulated signaling assemblies.A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells.Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged STAT activation through autocrine/paracrine stimulation in human primary T cells Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo.Regulation of T-cell antigen receptor-mediated inside-out signaling by cytosolic adapter proteins and Rap1 effector molecules.Signaling by small GTPases in the immune system.Annexin-A1: a pivotal regulator of the innate and adaptive immune systems.Spatial organization and signal transduction at intercellular junctions

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Positive and negative regulation of T-cell activation by adaptor proteins.

http://www.wikidata.org/entity/Q34572179

description

2001 nî lūn-bûn

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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

@zh-hk

2001年論文

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2001年論文

@zh-tw

2001年论文

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name

Positive and negative regulation of T-cell activation by adaptor proteins.

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Positive and negative regulation of T-cell activation by adaptor proteins.

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Positive and negative regulation of T-cell activation by adaptor proteins.

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type

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Positive and negative regulation of T-cell activation by adaptor proteins.

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Positive and negative regulation of T-cell activation by adaptor proteins.

@en

Positive and negative regulation of T-cell activation by adaptor proteins.

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prefLabel

Positive and negative regulation of T-cell activation by adaptor proteins.

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Positive and negative regulation of T-cell activation by adaptor proteins.

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Positive and negative regulation of T-cell activation by adaptor proteins.

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Nature Reviews Immunology

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Positive and negative regulation of T-cell activation by adaptor proteins.

@en

P2093

Koretzky GA

http://www.w3.org/2001/XMLSchema#string

Myung PS

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P2860

SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

Localized Rac activation dynamics visualized in living cells

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

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scholarly article

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10.1038/35100523

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2

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1

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11905825

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