Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. - sprookjes - yvandenbroek - TriplyDB

Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

http://www.wikidata.org/entity/Q34592093

about

RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth Emerging roles for the non-canonical IKKs in cancer The tumor suppressor PP2A Abeta regulates the RalA GTPase Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases Novel therapeutic targets for pancreatic cancer Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone Cancer of the Pancreas: Molecular Pathways and Current Advancement in Treatment Genetics and biology of pancreatic ductal adenocarcinoma The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression.Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformation Ral GTPases: crucial mediators of exocytosis and tumourigenesis Ral GTPases in tumorigenesis: emerging from the shadows Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I Synthesis of novel Ral inhibitors: An in vitro and in vivo study The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling Discovery and characterization of small molecules that target the GTPase Ral Ral-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migration.The Ral GTPase pathway in metastatic bladder cancer: key mediator and therapeutic target Phosphorylation of RalB is important for bladder cancer cell growth and metastasis RalBP1 is necessary for metastasis of human cancer cell lines Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76).Pancreatic cancer.Ras effector switching promotes divergent cell fates in C. elegans vulval patterning.Myo1c regulates lipid raft recycling to control cell spreading, migration and Salmonella invasion SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1 IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity.Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia.A novel approach to tag and identify geranylgeranylated proteins.Ral activation promotes melanomagenesis.Oncogenic KRAS signalling in pancreatic cancer.Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis.TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling.

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P2860

Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

http://www.wikidata.org/entity/Q34592093

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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type

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and R ...... an pancreatic carcinoma cells.

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Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells

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Channing J Der

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Christopher M Counter

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