Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.
about
Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosisFiloviral immune evasion mechanismsDRBP76 associates with Ebola virus VP35 and suppresses viral polymerase functionMutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcomeInfluenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-IEvasion of antiviral immunity through sequestering of TBK1/IKKε/IRF3 into viral inclusion bodiesThe tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral responseEbola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responsesIFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damageToscana virus NSs protein inhibits the induction of type I interferon by interacting with RIG-IFunction and regulation of retinoic acid-inducible gene-IPathogen recognition and inflammatory signaling in innate immune defensesCytosolic Innate Immune Sensing and Signaling upon InfectionAddressing the Complications of Ebola and Other Viral Hemorrhagic Fever Infections: Using Insights from Bacterial and Fungal SepsisResistance to Rhabdoviridae Infection and Subversion of Antiviral ResponsesTLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetesDifferential Induction of Type I Interferon Responses in Myeloid Dendritic Cells by Mosquito and Mammalian-Cell-Derived AlphavirusesCapsid Protein of Eastern Equine Encephalitis Virus Inhibits Host Cell Gene ExpressionDistinct RIG-I and MDA5 Signaling by RNA Viruses in Innate ImmunityProcessing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon InductionBlockade of virus infection by human CD4+ T cells via a cytokine relay networkNegative regulation of cytoplasmic RNA-mediated antiviral signalingMarburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola VirusModulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 proteinEbolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppressionStructure of the Ebola VP35 interferon inhibitory domainMutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea PigsStructural basis for dsRNA recognition and interferon antagonism by Ebola VP35Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory DomainStructural basis for Marburg virus VP35-mediated immune evasion mechanismsThe Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal FoldEbolavirus VP35 Coats the Backbone of Double-Stranded RNA for Interferon AntagonismDevelopment of RNA Aptamers Targeting Ebola Virus VP35In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor ActivityRIG-I in RNA virus recognitionViral evasion of intracellular DNA and RNA sensingRescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNAEbola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machineryBroad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses
P2860
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P2860
Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@ast
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@en
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@nl
type
label
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@ast
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@en
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@nl
prefLabel
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@ast
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@en
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@nl
P2860
P50
P356
P1433
P1476
Ebola virus VP35 protein binds ...... on induced by RIG-I signaling.
@en
P2093
Christopher R Kimberlin
Yueh-Ming Loo
P2860
P304
P356
10.1128/JVI.02199-05
P407
P50
P577
2006-06-01T00:00:00Z