Muscle giants: molecular scaffolds in sarcomerogenesis. - sprookjes - yvandenbroek - TriplyDB

Muscle giants: molecular scaffolds in sarcomerogenesis.

Muscle giants: molecular scaffolds in sarcomerogenesis.

http://www.wikidata.org/entity/Q34793699

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Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties α-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin Myosin binding protein C: implications for signal-transduction Large isoforms of UNC-89 (obscurin) are required for muscle cell architecture and optimal calcium release in Caenorhabditis elegans Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase.Targeting the sarcomere to correct muscle function The Longissimus and Semimembranosus muscles display marked differences in their gene expression profiles in pig Integrity of the network sarcoplasmic reticulum in skeletal muscle requires small ankyrin 1 The kinase domains of obscurin interact with intercellular adhesion proteins Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle.The nebulin SH3 domain is dispensable for normal skeletal muscle structure but is required for effective active load bearing in mouse.Genetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathy.Recent advances in muscle research Biophysical characterization of naturally occurring titin M10 mutations Influence of V54M mutation in giant muscle protein titin: a computational screening and molecular dynamics approach.In vitro Differentiation of Functional Human Skeletal Myotubes in a Defined System Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice.Extensive and modular intrinsically disordered segments in C. elegans TTN-1 and implications in filament binding, elasticity and oblique striation.Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy.Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo TGF-β1 enhances contractility in engineered skeletal muscle Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance Myosin binding protein-C slow: an intricate subfamily of proteins.Obscure functions: the location-function relationship of obscurins.Ab initio detection of fuzzy amino acid tandem repeats in protein sequences.Truncations of titin causing dilated cardiomyopathy.Independent evolution of striated muscles in cnidarians and bilaterians.Cardiomyocyte maturation: It takes a village to raise a kid.Probing muscle ankyrin-repeat protein (MARP) structure and function Contribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle.Scaffolds and chaperones in myofibril assembly: putting the striations in striated muscle.Obscurins: Goliaths and Davids take over non-muscle tissues.Two novel mutations in myosin binding protein C slow causing distal arthrogryposis type 2 in two large Han Chinese families may suggest important functional role of immunoglobulin domain C2.The desmin coil 1B mutation K190A impairs nebulin Z-disc assembly and destabilizes actin thin filaments.Myosin binding protein-C: a regulator of actomyosin interaction in striated muscle Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle.

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Muscle giants: molecular scaffolds in sarcomerogenesis.

http://www.wikidata.org/entity/Q34793699

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Muscle giants: molecular scaffolds in sarcomerogenesis.

@ast

Muscle giants: molecular scaffolds in sarcomerogenesis.

@en

Muscle giants: molecular scaffolds in sarcomerogenesis.

@nl

type

label

Muscle giants: molecular scaffolds in sarcomerogenesis.

@ast

Muscle giants: molecular scaffolds in sarcomerogenesis.

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Muscle giants: molecular scaffolds in sarcomerogenesis.

@nl

prefLabel

Muscle giants: molecular scaffolds in sarcomerogenesis.

@ast

Muscle giants: molecular scaffolds in sarcomerogenesis.

@en

Muscle giants: molecular scaffolds in sarcomerogenesis.

@nl

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PHYSREV.00017.2009

P1433

Physiological Reviews

P1476

Muscle giants: molecular scaffolds in sarcomerogenesis.

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P2093

Aikaterini Kontrogianni-Konstantopoulos

http://www.w3.org/2001/XMLSchema#string

Amber L Bowman

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Maegen A Ackermann

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Robert J Bloch

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Solomon V Yap

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P2860

Structural basis for activation of the titin kinase domain during myofibrillogenesis

The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity

When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin

A novel nemaline myopathy in the Amish caused by a mutation in troponin T1

The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies

Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly

Specific interaction of the potassium channel beta-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system

P304

1217-1267

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scholarly article

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10.1152/PHYSREV.00017.2009

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4

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89

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2009-10-01T00:00:00Z

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26856212

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19789381

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3076733

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