Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2 - sprookjes - yvandenbroek - TriplyDB

Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2

Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2

http://www.wikidata.org/entity/Q34891145

about

The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined Evolving concepts in cancer therapy through targeting sphingolipid metabolism Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.Dual inhibition of sphingosine kinase isoforms ablates TNF-induced drug resistance.Preferential star strand biogenesis of pre-miR-24-2 targets PKC-alpha and suppresses cell survival in MCF-7 breast cancer cells The impact of sphingosine kinase-1 in head and neck cancer.Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells.Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha.Diphenyl difluoroketone: a potent chemotherapy candidate for human hepatocellular carcinoma Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling.Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells.Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells.Down-regulation of NF kappa B activation is an effective therapeutic modality in acquired platinum-resistant bladder cancer Bee venom inhibits growth of human cervical tumors in mice A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations.Radiation, inflammation, and immune responses in cancer Targeting sphingosine-1-phosphate in hematologic malignancies Altered death receptor signaling promotes epithelial-to-mesenchymal transition and acquired chemoresistance.Pharmacology and anti-tumor activity of RWJ67657, a novel inhibitor of p38 mitogen activated protein kinase ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer.The role of sphingosine-1-phosphate in breast cancer tumor-induced lymphangiogenesis.Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation.The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition.Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors.Origin of aromatase inhibitory activity via proteochemometric modeling.Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells.DMS triggers apoptosis associated with the inhibition of SPHK1/NF-κB activation and increase in intracellular Ca2+ concentration in human cancer cells.A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms' tumor cells in vitro and in vivo.Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer.Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer.Role of nuclear factor-ĸB in breast and colorectal cancer.Oncogenic properties of sphingosine kinases in haematological malignancies.Sphingolipids and mitochondrial apoptosis.3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells.Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells.Honokiol targets mitochondria to halt cancer progression and metastasis.Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection.

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Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2

http://www.wikidata.org/entity/Q34891145

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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name

Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Targeting NFĸB mediated breast ...... bition of sphingosine kinase-2

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Barbara S Beckman

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Charles D Smith

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Evelyn M Slaughter

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Hafez S Khalili

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James W Antoon

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Jennifer L Driver

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Martin D White

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Matthew E Burow

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Steven Elliott

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Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells

Roles of bioactive sphingolipids in cancer biology and therapeutics

Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators

Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

Discovery and evaluation of inhibitors of human sphingosine kinase.

Apoptosis, p53, and tumor cell sensitivity to anticancer agents.

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2

A novel sphingosine kinase inhibitor induces autophagy in tumor cells.

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