Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
about
Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivoThe bridge helix coordinates movements of modules in RNA polymeraseThe Bridge Helix of RNA polymerase acts as a central nanomechanical switchboard for coordinating catalysis and substrate movementMolecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor proteinCrystal structure of the 14-subunit RNA polymerase IDivergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and IIThe nucleotide addition cycle of RNA polymerase is controlled by two molecular hinges in the Bridge Helix domainMillisecond dynamics of RNA polymerase II translocation at atomic resolutionTrigger loop folding determines transcription rate of Escherichia coli's RNA polymeraseStepwise mechanism for transcription fidelityMolecular evolution of multisubunit RNA polymerases: structural analysisConformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase.RNA polymerase II with open and closed trigger loops: active site dynamics and nucleic acid translocationRevealing the functions of TFIIB.Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.Modulation of RNA polymerase activity through the trigger loop foldingA bridge to transcription by RNA polymerase.Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation.CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.Ratcheting of RNA polymerase toward structural principles of RNA polymerase operations.High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.Energetic and structural details of the trigger-loop closing transition in RNA polymerase II.Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanismAllosteric control of catalysis by the F loop of RNA polymerase.Site-directed mutagenesis, purification and assay of Saccharomyces cerevisiae RNA polymerase II.Archaeal RNA polymerase.Cation-π interactions induce kinking of a molecular hinge in the RNA polymerase bridge-helix domain.RNA polymerase II transcription: structure and mechanismBasic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.Dynamics of pyrophosphate ion release and its coupled trigger loop motion from closed to open state in RNA polymerase II.High-throughput purification of affinity-tagged recombinant proteins.The linker domain of basal transcription factor TFIIB controls distinct recruitment and transcription stimulation functions.Role of the RNA polymerase trigger loop in catalysis and pausing.Activity map of the Escherichia coli RNA polymerase bridge helix.The RNA polymerase trigger loop functions in all three phases of the transcription cycle.Hinge action versus grip in translocation by RNA polymerase.
P2860
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P2860
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@ast
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@en
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@nl
type
label
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@ast
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@en
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@nl
prefLabel
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@ast
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@en
Bridge helix and trigger loop perturbations generate superactive RNA polymerases.
@nl
P2093
P2860
P356
P1433
P1476
Bridge helix and trigger loop perturbations generate superactive RNA polymerases
@en
P2093
Dominika Trzaska
Hannah C Carney
Simone Wiesler
P2860
P356
10.1186/JBIOL98
P577
2008-12-02T00:00:00Z