Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins - sprookjes - yvandenbroek - TriplyDB

Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

http://www.wikidata.org/entity/Q35002854

about

Characterization and Functions of Protease-Activated Receptor 2 in Obesity, Diabetes, and Metabolic Syndrome: A Systematic Review Turning receptors on and off with intracellular pepducins: new insights into G-protein-coupled receptor drug development Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.Suppression of arterial thrombosis without affecting hemostatic parameters with a cell-penetrating PAR1 pepducin.Protease-activated receptor-2 modulates protease-activated receptor-1-driven neointimal hyperplasia.Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis.β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis.Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering.Cofactoring and dimerization of proteinase-activated receptors Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impact Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein.Coagulation, protease-activated receptors, and viral myocarditis.Biased signalling and proteinase-activated receptors (PARs): targeting inflammatory disease.Pharmacology of antiplatelet agents.Biased signaling of protease-activated receptors.Endothelial barrier dysfunction in septic shock.Integration of endothelial protease-activated receptor-1 inflammatory signaling by ubiquitin.Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Proteinases, Their Extracellular Targets, and Inflammatory Signaling.Homeostatic effects of coagulation protease-dependent signaling and protease activated receptors.Pepducins and Other Lipidated Peptides as Mechanistic Probes and Therapeutics.Down-regulation of PAR1 activity with a pHLIP-based allosteric antagonist induces cancer cell death.Targeting Liver Fibrosis with a Cell-penetrating Protease-activated Receptor-2 (PAR2) Pepducin.Pharmacological Targeting of Protease-Activated Receptor 2 Affords Protection from Bleomycin-Induced Pulmonary Fibrosis.Functional inhibition of PAR2 alleviates allergen-induced airway hyperresponsiveness and inflammation.Proteinase-activated receptor 2 (PAR(2)) in cholangiocarcinoma (CCA) cells: effects on signaling and cellular level.The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

P2860

Q26752383-28337E06-495E-4046-B98B-E25E8413BBFB Q27024397-28B5F6B9-BDF0-4783-BBF9-818C5BAD9BB6 Q27027602-EAFD52D7-D304-4414-9417-42E460ED314E Q30486707-92D4E0AD-F712-491C-9D7C-00DDAC8BEC39 Q33898352-3DFDDBA0-45CE-49A0-8B95-A8764AF20384 Q34091200-09855D5F-D6F4-4BA8-B813-3D3D30E901F0 Q34282119-DD83C194-FC4F-4EE3-86A5-8C32BE1121A2 Q35620514-4A356EF5-3094-458F-964C-6F1058DC87E4 Q35695573-E72FBE75-CC83-4F4B-B77C-942E9A77832B Q35860717-C63A1536-6554-49AF-B66B-11642C4C8880 Q36170226-824CE9E3-6983-4D16-BB58-8236CC905B35 Q36322931-7272DBB6-FFDD-4183-8ED3-BDFE021705B6 Q36339904-25D6749A-59FF-448D-AF5A-EB8BEF11A15B Q36699691-5C23239E-51B0-4290-B500-47989C0329B3 Q36710897-01652AC3-22AF-4233-94B4-D54700852237 Q37236116-00EBE01D-C5E7-49E1-8794-C12FB96CD759 Q37348262-9AB7BD5B-CBCA-46CD-BCCA-13E507ACB03E Q37421226-E2ED361E-659E-4B62-88B4-82D344140AB6 Q37619823-F4AB5313-FEFC-4C59-81CC-CA32C372A9E0 Q37635262-92555E6F-2435-4FAB-9034-4CF91A183F0E Q38154211-338592D8-5509-4B1A-9E5D-9A358B3CB0D9 Q38214613-C20F9AA0-82F5-4F02-B542-88CDF4F85418 Q38270705-41D27AD6-03F2-456C-9CED-79BF6EF8E40B Q38723122-0768AB17-C0E7-4493-B1F7-5E0ACBAEE9E9 Q38758445-747824A8-AC0A-4FB0-AB95-30BE08D193AD Q38966192-D7792F08-B668-43BC-AB24-0B544B5CBB94 Q39410950-9C38E8E0-481C-47B9-BE2F-0C8BD9DE0351 Q40405065-408530FE-786C-4BC3-AE55-0CA7AECBF52E Q42066943-7740A5E0-591C-45F9-8FBC-46AA6B92C7B0 Q42725773-CD738232-E922-4F6F-A009-DC5B67EF7938 Q43159978-E756A4A4-1691-4E4E-AF74-01BC917F7C7A Q45980761-BB2B1A27-2659-4AA5-9070-82C56CFF06D7 Q54490877-BCD821B1-3F4A-4267-A1B2-B76B8863DA74 Q55031114-6BDC2CA7-4DEC-4E73-A94A-4C74C41E09D4 Q58737553-E9F174EA-C081-4682-A30F-BE51BB614134

P2860

Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

http://www.wikidata.org/entity/Q35002854

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Interdicting protease-activate ...... ith cell-penetrating pepducins

@ast

Interdicting protease-activate ...... ith cell-penetrating pepducins

@en

type

label

Interdicting protease-activate ...... ith cell-penetrating pepducins

@ast

Interdicting protease-activate ...... ith cell-penetrating pepducins

@en

prefLabel

Interdicting protease-activate ...... ith cell-penetrating pepducins

@ast

Interdicting protease-activate ...... ith cell-penetrating pepducins

@en

P1433

Q35002854-211319B8-0A23-4636-B469-8ED323B4AAC5

P1476

Q35002854-72252C92-4093-4483-9ABF-8FC2FB578EE7

P2093

Q35002854-0AA6FADD-C21A-4539-888F-E5ABDFFB0E14

Q35002854-1031A089-BF1C-42BD-BB8D-A024F67AA17C

Q35002854-48E8CDAC-1D9D-4F7F-89B8-62D32B7EFD9B

Q35002854-627AA56A-2DC5-474D-B6CE-061BCF164332

Q35002854-C47872AD-042F-4239-A624-6C7FE4465B2A

Q35002854-F7303102-2E49-424D-9CA3-3337E114C7BB

Q35002854-FF14AB1F-E8E4-4D09-9F06-0209FC28DADA

P2860

Q35002854-0605BF1F-4693-48ED-B45B-C1FB7A8E79C6

Q35002854-0743BC97-4CDD-4292-BAAA-C840FF0F30C9

Q35002854-0C900A21-8E93-495D-8174-60AB0A021D22

Q35002854-0FB54877-5E3E-48B4-A4F6-D4A5278CF2BE

Q35002854-130BED32-4F45-4622-ACE1-F1842BE3BBB2

Q35002854-14B6485E-9EE8-437F-A53B-1C449A68848A

Q35002854-19B5E2E5-97D0-42E1-9C93-0D1D33E829D9

Q35002854-1A5E0F44-97FF-4E0A-B8FB-8A8569AB39AC

Q35002854-1AF0E7B8-D965-4891-B8E0-6B84EDDF2700

Q35002854-3A3F997B-1CBB-4995-9672-770E5FAD30BB

P304

Q35002854-290D0993-0F88-4BA2-88AB-AD84A43C0C4E

P31

Q35002854-6338B71A-7443-460A-975A-0E9B8D950569

P356

Q35002854-95A77490-E551-48BD-BD3E-52F2C2AD50B1

P407

Q35002854-A3F1A0C8-6377-41AA-B05E-EA303FAC9CF8

P433

Q35002854-6E5F0961-77B5-4A7A-9F91-14E06D70A361

P478

Q35002854-F634FB27-54A5-4AAE-8692-9433F1B85721

P577

Q35002854-FF1D0ABD-D95E-48D5-9FDF-587E77CD6687

P5875

Q35002854-136B05FC-C863-4C40-BED7-82288EE2EB44

P698

Q35002854-97F638CA-60BE-4741-BCA3-64480ED5D561

P921

Q35002854-5CC9A025-42F8-49EB-B3C1-6BDD12DEBBCE

P932

Q35002854-195314C6-E31A-4E22-9CDA-C237C931CE97

P356

PNAS.1017091108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Interdicting protease-activate ...... ith cell-penetrating pepducins

@en

P2093

Andrew Bohm

http://www.w3.org/2001/XMLSchema#string

Athan Kuliopulos

http://www.w3.org/2001/XMLSchema#string

George Perides

http://www.w3.org/2001/XMLSchema#string

Katherine Lazarides

http://www.w3.org/2001/XMLSchema#string

Leila M Sevigny

http://www.w3.org/2001/XMLSchema#string

Lidija Covic

http://www.w3.org/2001/XMLSchema#string

Ping Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization

Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides

Molecular cloning of a potential proteinase activated receptor

Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2

Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)

Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis

Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1

Protease-activated receptor 2 mediates the proinflammatory effects of synovial mast cells.

P304

8491-8496

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1017091108

http://www.w3.org/2001/XMLSchema#string

P407

P433

20

http://www.w3.org/2001/XMLSchema#string

P478

108

http://www.w3.org/2001/XMLSchema#string

P577

2011-05-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51092907

http://www.w3.org/2001/XMLSchema#string

P698

21536878

http://www.w3.org/2001/XMLSchema#string

P921

P932

3100971

http://www.w3.org/2001/XMLSchema#string