Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
about
Melanoma: from melanocyte to genetic alterations and clinical optionsTargeting the CCL2-CCR2 signaling axis in cancer metastasisCellular senescence in aging and age-related disease: from mechanisms to therapyPleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationPathways and therapeutic targets in melanomaRoles and mechanisms of cellular senescence in regulation of tissue homeostasisIn vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells.DNA Damage: From Chronic Inflammation to Age-Related DeteriorationSIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells.An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.Cellular senescence and protein degradation: breaking down cancerDiallyl disulfide inhibits TNFα-induced CCL2 release by MDA-MB-231 cells.Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.SIRT1 suppresses the senescence-associated secretory phenotype through epigenetic gene regulation.Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patientsMicrobiome and cancer.Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cellsTumor protein p63/nuclear factor κB feedback loop in regulation of cell death.Molecular damage in cancer: an argument for mTOR-driven agingIs the induction of tumor cell senescence the key to a good irradiated tumor vaccine?Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine.MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory PhenotypeChromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.PARP1 Inhibitors: antitumor drug design.Differential secretome analysis reveals CST6 as a suppressor of breast cancer bone metastasisAurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.TBX2 expression is regulated by PAX3 in the melanocyte lineageNF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug.Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells.Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populationsFrom Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.Wnt signaling potentiates nevogenesisA senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses.P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescenceBeyond DNA Repair: Additional Functions of PARP-1 in Cancer.
P2860
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P2860
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@ast
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@en
type
label
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@ast
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@en
prefLabel
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@ast
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@en
P2093
P2860
P50
P356
P1433
P1476
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)
@en
P2093
Brigitte Bressac-de Paillerets
Caroline Bonet
Caroline Robert
Jean-François Peyron
Jean-Philippe Lacour
Karine Bille
Mickaël Ohanna
Paul Hofman
Sandy Giuliano
Stéphane Rocchi
P2860
P304
P356
10.1101/GAD.625811
P577
2011-06-06T00:00:00Z