Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.
about
Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosisIdentification of STAT3 as a substrate of receptor protein tyrosine phosphatase TSTAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancerTargeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solutionChemical probes that competitively and selectively inhibit Stat3 activationA novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel DiseaseNSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3Suppressor of cytokine signaling 3 (SOCS3) is not an independent biomarker of colorectal adenoma risk.S-phase cell cycle arrest, apoptosis, and molecular mechanisms of aplasia ras homolog member I-induced human ovarian cancer SKOV3 cell lines.Adapter protein Shc regulates Janus kinase 3 phosphorylationS1pping fire: Sphingosine-1-phosphate signaling as an emerging target in inflammatory bowel disease and colitis-associated cancerA STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation.Genome-wide uncovering of STAT3-mediated miRNA expression profiles in colorectal cancer cell lines.Synthesis and Biological Evaluation of Novel N-phenyl-5-carboxamidyl Isoxazoles as Potential Chemotherapeutic Agents for Colon Cancer.Identification of molecular switch regulating interactions of Janus kinase 3 with cytoskeletal proteins.A systems biology approach to the global analysis of transcription factors in colorectal cancer.Role of Janus kinase 3 in mucosal differentiation and predisposition to colitisLuteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.Janus kinase 3 regulates interleukin 2-induced mucosal wound repair through tyrosine phosphorylation of villin.HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells.Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway.STAT3 is necessary for proliferation and survival in colon cancer-initiating cells.Propolis augments apoptosis induced by butyrate via targeting cell survival pathways.Myeloid cell leukemia-1 is associated with tumor progression by inhibiting apoptosis and enhancing angiogenesis in colorectal cancer.Prognostic significance of STAT3 and phosphorylated STAT3 in human soft tissue tumors - a clinicopathological analysisAn association study of polymorphisms in JAK3 gene with lung cancer in the Korean population.Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030.Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells.ING4 enhances paclitaxel's effect on colorectal cancer growth in vitro and in vivoSPARC expression induces cell cycle arrest via STAT3 signaling pathway in medulloblastoma cells.STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferationLPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways.Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells.Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells.Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathwayScutellaria barbata D. Don inhibits growth and induces apoptosis by suppressing IL-6-inducible STAT3 pathway activation in human colorectal cancer cells.
P2860
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P2860
Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@ast
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@en
type
label
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@ast
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@en
prefLabel
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@ast
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@en
P2093
P2860
P1476
Constitutive activation of JAK ...... rest of colon carcinoma cells.
@en
P2093
Changping Li
George Z Rassidakis
Hesham M Amin
Ioannis Grammatikakis
Keita Kunisada
Lucian R Chirieac
Raymond Lai
Stanley R Hamilton
Vilmos A Thomazy
P2860
P304
P356
10.1016/S0002-9440(10)61187-X
P407
P577
2005-10-01T00:00:00Z