Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain. - sprookjes - yvandenbroek - TriplyDB

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

http://www.wikidata.org/entity/Q35108014

about

Chemical genetics approaches for selective intervention in epigenetics A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing Identification and Structure-Activity Relationship Studies of Small-Molecule Inhibitors of the Methyllysine Reader Protein Spindlin1.Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes.Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7.Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis.CBX Chromodomain Inhibition Enhances Chemotherapy Response in Glioblastoma Multiforme.Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family Selective targeting of epigenetic reader domains.Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains.Structural aspects of small-molecule inhibition of methyllysine reader proteins.Chemical probes for methyl lysine reader domains H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.A 16 Yin Yang gene expression ratio signature for ER+/node- breast cancer.Writing, erasing and reading histone lysine methylations.Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation.Molecular structures guide the engineering of chromatin.Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration.The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia.Structure–Activity Relationships of Cbx7 Inhibitors, Including Selectivity Studies against Other Cbx Proteins.Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation

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Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

http://www.wikidata.org/entity/Q35108014

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

@wuu

name

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

@ast

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

@en

type

label

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

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Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

@en

prefLabel

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

@ast

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

@en

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J.CHEMBIOL.2014.11.021

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Chemistry and Biology

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Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

@en

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Alexander N Plotnikov

http://www.w3.org/2001/XMLSchema#string

Jean Jakoncic

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Jiaojie Li

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Keita Morohashi

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Lei Zeng

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Martin Walsh

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Ming-Ming Zhou

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Steven G Smith

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Vivian Stojanoff

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Yoel Rodriguez

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Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression

Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases

Recognition and Specificity Determinants of the Human Cbx Chromodomains

The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site

Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7)

Polycomb CBX7 has a unifying role in cellular lifespan

The INK4a/ARF network in tumour suppression

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10.1016/J.CHEMBIOL.2014.11.021

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2015-02-05T00:00:00Z

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