Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
about
Mechanisms of CaMKII action in long-term potentiationThe synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degenerationUltrastructural abnormalities in CA1 hippocampus caused by deletion of the actin regulator WAVE-1Improving a natural CaMKII inhibitor by random and rational designCaMKII binding to GluN2B is critical during memory consolidationExcitotoxic insult results in a long-lasting activation of CaMKIIα and mitochondrial damage in living hippocampal neuronsProtection of α-CaMKII from Dephosphorylation by GluN2B Subunit of NMDA Receptor Is Abolished by Mutation of Glu96 or His282 of α-CaMKIISurface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapsesSorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's diseaseFast Decay of CaMKII FRET Sensor Signal in Spines after LTP Induction Is Not Due to Its Dephosphorylation.Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.A significant but rather mild contribution of T286 autophosphorylation to Ca2+/CaM-stimulated CaMKII activity.Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model.Effect of multimeric structure of CaMKII in the GluN2B-mediated modulation of kinetic parameters of ATP.Genetic inhibition of CaMKII in dorsal striatal medium spiny neurons reduces functional excitatory synapses and enhances intrinsic excitability.On the mechanism of synaptic depression induced by CaMKIIN, an endogenous inhibitor of CaMKII.The initiation of synaptic 2-AG mobilization requires both an increased supply of diacylglycerol precursor and increased postsynaptic calcium.Efficacy of lovastatin on learning and memory deficits caused by chronic intermittent hypoxia-hypercapnia: through regulation of NR2B-containing NMDA receptor-ERK pathway.Nucleotides and phosphorylation bi-directionally modulate Ca2+/calmodulin-dependent protein kinase II (CaMKII) binding to the N-methyl-D-aspartate (NMDA) receptor subunit GluN2B.Kinetic memory based on the enzyme-limited competitionCatalytically Dead αCaMKII K42M Mutant Acts as a Dominant Negative in the Control of Synaptic Strength.Activity-dependent regulation of synaptic strength by PSD-95 in CA1 neuronsSubstrate-selective and calcium-independent activation of CaMKII by α-actinin.Bi-directional regulation of CaMKIIα phosphorylation at Thr286 by NMDA receptors in cultured cortical neuronsPossible Signaling Pathways Mediating Neuronal Calcium Sensor-1-Dependent Spatial Learning and Memory in MiceCaMKII regulation in information processing and storage.Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic PlasticityDiversity in NMDA receptor composition: many regulators, many consequences.The CaMKII/NMDAR complex as a molecular memoryActivated CaMKII couples GluN2B and casein kinase 2 to control synaptic NMDA receptors.Persistent reversal of enhanced amphetamine intake by transient CaMKII inhibitionThe delicate bistability of CaMKIIPhosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus ReconsolidationCdk5 Modulates Long-Term Synaptic Plasticity and Motor Learning in Dorsolateral StriatumRecombinant probes reveal dynamic localization of CaMKIIα within somata of cortical neurons.Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B.Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference.Activation-triggered subunit exchange between CaMKII holoenzymes facilitates the spread of kinase activityRefreshing memories.CaMKII activity in the ventral tegmental area gates cocaine-induced synaptic plasticity in the nucleus accumbens.
P2860
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P2860
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@ast
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@en
type
label
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@ast
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@en
prefLabel
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@ast
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@en
P2093
P2860
P1476
Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength
@en
P2093
German Fernandez-Villalobos
Gyulnara Kasumova
Ivar S Stein
Johannes W Hell
John Lisman
K Ulrich Bayer
Magdalena Sanhueza
Nikolai Otmakhov
Peng Zhang
P2860
P304
P356
10.1523/JNEUROSCI.1250-11.2011
P407
P577
2011-06-01T00:00:00Z