Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.
about
Revisiting the case for genetically engineered mouse models in human myelodysplastic syndrome researchFbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis.Combining small molecules for cell reprogramming through an interatomic analysis.High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche.Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow CompartmentsOsteoclasts and hematopoiesis.Modeling human hematopoietic stem cell biology in the mouse.The hematopoietic stem-cell niche in health and leukemia.The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis.Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors.The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells.A myeloid tumor suppressor role for NOL3Somatic mutation of CDKN1B in small intestine neuroendocrine tumors.Low CREBBP expression is associated with adverse long-term outcomes in paediatric acute lymphoblastic leukaemia.Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apcdel/+ MDS mouse model.The Bone Marrow Microenvironment for Hematopoietic Stem Cells.
P2860
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P2860
Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Crebbp haploinsufficiency in m ...... ls and excessive myelopoiesis.
@ast
Crebbp haploinsufficiency in m ...... ls and excessive myelopoiesis.
@en
type
label
Crebbp haploinsufficiency in m ...... ls and excessive myelopoiesis.
@ast
Crebbp haploinsufficiency in m ...... ls and excessive myelopoiesis.
@en
prefLabel
Crebbp haploinsufficiency in m ...... ls and excessive myelopoiesis.
@ast
Crebbp haploinsufficiency in m ...... ls and excessive myelopoiesis.
@en
P2093
P2860
P1433
P1476
Crebbp haploinsufficiency in m ...... lls and excessive myelopoiesis
@en
P2093
Andrei V Krivtsov
David M Livingston
Diane Horn
Mike Lecocke
Ruth White
Scott A Armstrong
Sherry L Abboud-Werner
Stephanie N Zimmer
P2860
P356
10.1182/BLOOD-2010-09-307942
P407
P577
2011-05-09T00:00:00Z