Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects - sprookjes - yvandenbroek - TriplyDB

Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

http://www.wikidata.org/entity/Q35119948

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Role of the MPTP in conditioning the heart - translatability and mechanism Differential Role of Leptin and Adiponectin in Cardiovascular System Leptin and its cardiovascular effects: Focus on angiogenesis Diabetic cardiomyopathy: signaling defects and therapeutic approaches Leptin protects H9c2 rat cardiomyocytes from H2O2-induced apoptosis Leptin protects cardiomyocytes from serum-deprivation-induced apoptosis by increasing anti-oxidant defence.Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells.The role of selected adipokines and ghrelin in the prognosis after myocardial infarction in a 12-month follow-up in the presence of metabolic syndrome.The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling Adipose tissue and vascular inflammation in coronary artery disease.The novel adipocytokine visfatin exerts direct cardioprotective effects Cardiac remodeling in obesity.Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore.Leptin stimulates sympathetic axon outgrowth Mechanisms of heart failure in obesity.The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities.Association of low leptin with cardiovascular events and mortality in patients with stable coronary artery disease: the Heart and Soul Study.Central leptin signaling is required to normalize myocardial fatty acid oxidation rates in caloric-restricted ob/ob mice.Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection.Serum Leptin Levels and the Risk of Stroke: The Framingham Study.Obesity, Inflammation and Acute Myocardial Infarction - Expression of leptin, IL-6 and high sensitivity-CRP in Chennai based population Influence of tumour necrosis factor alpha on the outcome of ischaemic postconditioning in the presence of obesity and diabetes.Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades.Effects of leptin on cardiovascular physiology Obesity improves myocardial ischaemic tolerance and RISK signalling in insulin-insensitive rats.Smoking Functions as a Negative Regulator of IGF1 and Impairs Adipokine Network in Patients with Rheumatoid Arthritis Detrimental effects of leptin on intracerebral hemorrhage via the STAT3 signal pathway.Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease.Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity Signalling mechanisms underlying the metabolic and other effects of adipokines on the heart.Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice Protective ischaemia in patients: preconditioning and postconditioning.Pathological ventricular remodeling: mechanisms: part 1 of 2 Reductions in mitochondrial O(2) consumption and preservation of high-energy phosphate levels after simulated ischemia in chronic hibernating myocardium.The Akt1 isoform is an essential mediator of ischaemic preconditioning Myocardial ischemic postconditioning against ischemia-reperfusion is impaired in ob/ob mice.Leptin signaling in the failing and mechanically unloaded human heart.Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets.Cardiometabolic comorbidities and rheumatic diseases: focus on the role of fat mass and adipokines.

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P2860

Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

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2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

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Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

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Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

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Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

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British Journal of Pharmacology

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Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

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P2093

A M Wynne

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C C T Smith

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D M Yellon

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J C Simpkin

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M M Mocanu

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S M Davidson

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P2860

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Rat heart is a site of leptin production and action

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo.

Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury.

Preconditioning protects by inhibiting the mitochondrial permeability transition.

Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection.

Adiponectin-mediated modulation of hypertrophic signals in the heart

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

Apoptosis in myocardial ischemia-reperfusion.

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16847434

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