Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
about
Modeling Kidney Disease with iPS CellsRole of the Polycystins in Cell Migration, Polarity, and Tissue MorphogenesisA polycystin-centric view of cyst formation and disease: the polycystins revisitedAutosomal dominant polycystic kidney disease: recent advances in clinical managementThe native TRPP2-dependent channel of murine renal primary ciliaTrafficking to the primary cilium membrane.Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver DiseaseVasopressin and disruption of calcium signalling in polycystic kidney disease.Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS sitemTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex.The Polycystin-1, Lipoxygenase, and α-Toxin Domain Regulates Polycystin-1 Trafficking.Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD.Progress in ciliary ion channel physiology.Isolated polycystic liver disease genes define effectors of polycystin-1 function.Tubby family proteins are adapters for ciliary trafficking of integral membrane proteinsStructural studies of the C-terminal tail of polycystin-2 (PC2) reveal insights into the mechanisms used for the functional regulation of PC2.PKD2-Related Autosomal Dominant Polycystic Kidney Disease: Prevalence, Clinical Presentation, Mutation Spectrum, and Prognosis.Calcium channels in primary cilia.Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney DiseasePrimary Cilia in Cystic Kidney Disease.Polycystin and calcium signaling in cell death and survival.The Sorting Nexin 3 Retromer Pathway Regulates the Cell Surface Localization and Activity of a Wnt-Activated Polycystin Channel Complex.The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR.Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.A potentially crucial role of the PKD1 C-terminal tail in renal prognosis.Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases.Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.The Genetic and Cellular Basis of Autosomal Dominant Polycystic Kidney Disease-A Primer for Clinicians.Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease.Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model.Monoallelic Mutations to DNAJB11 Cause Atypical Autosomal-Dominant Polycystic Kidney Disease.Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification.The role of transient receptor potential polycystin channels in bone diseases
P2860
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P2860
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@ast
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@en
type
label
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@ast
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@en
prefLabel
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@ast
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@en
P2093
P2860
P356
P1476
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
@en
P2093
Christopher J Ward
Cynthia J Hommerding
Katharina Hopp
Peter C Harris
Vladimir G Gainullin
P2860
P304
P356
10.1172/JCI76972
P407
P577
2015-01-09T00:00:00Z