Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans
about
Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapyExtracellular vesicles round off communication in the nervous systemDrug repositioning approaches for the discovery of new therapeutics for Alzheimer's diseaseMonoaminergic and Histaminergic Strategies and Treatments in Brain DiseasesNeuronal clearance of amyloid-β by endocytic receptor LRP1.Investigational drugs for treating agitation in persons with dementia.Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's diseaseFluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice.A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets.Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisNeuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.Depressive Symptoms in Clinical and Incipient Alzheimer's Disease.Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.Role of citalopram in the treatment of agitation in Alzheimer's disease.An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.A depressive endophenotype of mild cognitive impairment and Alzheimer's diseaseSpecific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice.Characterization of a brain permeant fluorescent molecule and visualization of Aβ parenchymal plaques, using real-time multiphoton imaging in transgenic micePotential natural products for Alzheimer's disease: targeted search using the internal ribosome entry site of tau and amyloid-β precursor protein.Amyloid deposition in Parkinson's disease and cognitive impairment: a systematic review.Sleep disturbances in Alzheimer's and Parkinson's diseases.Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.Alzheimer's disease and gut microbiota.Serotonin 6 receptor controls Alzheimer's disease and depressionCerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers.Amyloid Hypothesis: Is There a Role for Antiamyloid Treatment in Late-Life Depression?ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model.Cerebral amyloid deposition and serotoninergic innervation in Parkinson disease.Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo.Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β pathwayThe serotonergic system and cognitive functionFluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1.Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease.Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment.Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease.Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.A review: treatment of Alzheimer's disease discovered in repurposed agents.
P2860
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P2860
Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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name
Serotonin signaling is associa ...... in transgenic mice and humans
@ast
Serotonin signaling is associa ...... in transgenic mice and humans
@en
type
label
Serotonin signaling is associa ...... in transgenic mice and humans
@ast
Serotonin signaling is associa ...... in transgenic mice and humans
@en
prefLabel
Serotonin signaling is associa ...... in transgenic mice and humans
@ast
Serotonin signaling is associa ...... in transgenic mice and humans
@en
P2093
P2860
P50
P356
P1476
Serotonin signaling is associa ...... in transgenic mice and humans
@en
P2093
Anshul Sathyan
Brianne M Disabato
Davinder Hayreh
Deborah K Verges
Gina D'Angelo
Hyejin Yoon
Jessica L Restivo
John R Cirrito
Jungsu Kim
Tammie Benzinger
P2860
P304
14968-14973
P356
10.1073/PNAS.1107411108
P407
P577
2011-08-22T00:00:00Z