Multiple functional domains of Tat, the trans-activator of HIV-1, defined by mutational analysis
about
The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SKThe Glutamine-rich Region of the HIV-1 Tat Protein Is Involved in T-cell ApoptosisTranscriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoterAnalysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat proteinHIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox stateThe HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase IICrystal structure of HIV-1 Tat complexed with human P-TEFbThe human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzymeRegulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factorsAkt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapyInteractions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivatorIn vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAPMolecular cloning and characterization of a cellular protein that interacts with the human immunodeficiency virus type 1 Tat transactivator and encodes a strong transcriptional activation domainThe human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for functionHIV-1 Tat interacts with LIS1 proteinHigher transactivation activity associated with LTR and Tat elements from HIV-1 BF intersubtype recombinant variantsThe cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disordersThe HIV-1 transcriptional activator Tat has potent nucleic acid chaperoning activities in vitroHomonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal proteinDSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongationA second-site mutation that restores replication of a Tat-defective human immunodeficiency virusRegulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication.Random mutagenesis of the human immunodeficiency virus type-1 trans-activator of transcription (HIV-1 Tat).Generation of West Nile virus infectious clones containing amino acid insertions between capsid and capsid anchor.HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.Multifaceted activities of the HIV-1 transactivator of transcription, Tat.Activity of synthetic tat peptides in human immunodeficiency virus type 1 long terminal repeat-promoted transcription in a cell-free system.Diametrically opposed effects of hypoxia and oxidative stress on two viral transactivatorsSequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro.Functional comparison of the basic domains of the Tat proteins of human immunodeficiency virus types 1 and 2 in trans activation.HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter.An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.CD39 is an ecto-(Ca2+,Mg2+)-apyrase.Fusion with an RNA binding domain to confer target RNA specificity to an RNase: design and engineering of Tat-RNase H that specifically recognizes and cleaves HIV-1 RNA in vitro.The activation region of the Tat protein of human immunodeficiency virus type-1 functions in yeast.Exon2 of HIV-2 Tat contributes to transactivation of the HIV-2 LTR by increasing binding affinity to HIV-2 TAR RNA.Effect on HIV-1 gene expression, Tat-Vpr interaction and cell apoptosis by natural variants of HIV-1 Tat exon 1 and Vpr from Northern IndiaCelastrol inhibits Tat-mediated human immunodeficiency virus (HIV) transcription and replication.
P2860
Q21136168-CE2C3863-67B5-45C5-8201-E75AD2B3E6E1Q22248069-65107B69-DEDF-4640-A6F7-2344E8F6CED0Q24523709-8AA698B1-34A7-48C7-90E2-691336BFB176Q24527261-7368BB4B-2BC4-42A6-8E11-0CF828F3BA31Q24561778-23347CD8-A237-4DB2-BB6F-98A177091C39Q24568360-F950409E-9A3C-491A-AFFD-951FC53AABF2Q24605935-3D1400F8-9BE8-43DF-BD3E-969DE7F3BF34Q24634569-FC0E09FB-25CE-4180-AD0D-B36F5D9B5073Q24646774-ADCDC1E1-4DCB-4499-B7B2-CD2E4DEFA392Q24651506-B6B0BE63-3096-41C5-BCA2-24B87351187BQ24655510-F77A19F5-E6AD-4507-9982-FC55287931A8Q24671522-0FC6C483-3379-4FD1-9846-6CB7CE5FE22AQ24675459-76A9BA77-7E26-4D1C-9B93-4C211C09C703Q24675484-9699B3F8-5FD5-4D7A-A7BA-A8863B47091FQ24682531-CBF2D56D-C6B7-4EEA-88A8-43923920A7F3Q24807276-507B6381-B49A-4DA1-A68C-31058E74B9C7Q25256833-0CB45600-F24D-4927-B393-7201B8F83762Q26777952-3D42F6DA-FF8D-4EE7-91FE-980CF544C7D5Q27486255-212DBB42-14D9-4BFB-B52A-D0F38697A12BQ27637986-97B3B8F5-ACF1-4BFE-B643-CE6518B1DCA0Q28139929-E82E5145-A9D5-47E3-B9E9-1FD69E745B1FQ30321811-925F3589-66D4-4B44-AB93-6391DD6B101DQ30350982-0F02AC2D-673B-49DE-9F3B-D6C38E56CB91Q30962300-1C3BEB27-78DA-4019-8CD4-218A6C722F1DQ33192810-1EE041D6-CE88-4C0E-B503-EF7D9CB984AAQ33584783-53A1E7AE-E791-4B83-84D9-BFE41A5EF53CQ33678960-F2090D30-0AE7-4B9F-9051-33954B4FA6B7Q33743566-BA7BA02C-A996-4B23-BE43-0396B146B454Q33787595-12613A48-AC9B-4941-B523-05F3F1878199Q33869031-C4A94F08-8841-4E5D-9EDF-549CE9219DB0Q33900660-535E0E88-9572-4521-9138-249ED559D8F2Q33930854-D8E024F7-E1CB-431D-885B-F3527735EA98Q34120071-9934B0E2-7D62-4FCE-8525-9BF651B31555Q34289422-A51C921A-6D47-49E2-BD74-C608ADF48CC5Q34378982-2E38F28E-15C6-4020-9EFD-B92742EC3BA7Q34595695-60E5B30D-B311-46E5-976C-4CEB745587ABQ34823344-8EB9F30E-AAB4-499F-A8F4-BBCC55C6EA93Q34888756-1EF36504-A116-433C-96AE-35410E016A70Q35075250-013D028C-4064-4595-AC05-DDA490F2A9F1Q35119118-CA52383C-0659-4DBA-BC98-B6C9E2E99178
P2860
Multiple functional domains of Tat, the trans-activator of HIV-1, defined by mutational analysis
description
1989 nî lūn-bûn
@nan
1989 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Multiple functional domains of ...... defined by mutational analysis
@ast
Multiple functional domains of ...... defined by mutational analysis
@en
type
label
Multiple functional domains of ...... defined by mutational analysis
@ast
Multiple functional domains of ...... defined by mutational analysis
@en
prefLabel
Multiple functional domains of ...... defined by mutational analysis
@ast
Multiple functional domains of ...... defined by mutational analysis
@en
P2093
P2860
P356
P1476
Multiple functional domains of ...... defined by mutational analysis
@en
P2093
A Srinivasan
G Chinnadurai
M Kuppuswamy
T Subramanian
P2860
P304
P356
10.1093/NAR/17.9.3551
P407
P577
1989-05-01T00:00:00Z