Involvement of chymase-mediated angiotensin II generation in blood pressure regulation. - sprookjes - yvandenbroek - TriplyDB

Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

http://www.wikidata.org/entity/Q35233098

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Direct evidence for intrarenal chymase-dependent angiotensin II formation on the diabetic renal microvasculature.Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis.Mast cell proteases as pharmacological targets Mast cell tryptases and chymases in inflammation and host defense.Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.Inflammatory Cell Infiltrates in Acute and Chronic Thoracic Aortic Dissection.Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor Impact of Mast Cell Chymase on Renal Disease Progression.Chymase mediates angiotensin-(1-12) metabolism in normal human hearts.IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction.Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer 344 × Brown Norway Rats.Role of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart Failure Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism.Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-γ.Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I The renin-angiotensin system and diabetes: an update.Alpha 2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generating activity.Intracrine angiotensin II functions originate from noncanonical pathways in the human heart.Big ET-1 processing into vasoactive peptides in arteries and veins.Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis.Salt-dependent inhibition of epithelial Na+ channel-mediated sodium reabsorption in the aldosterone-sensitive distal nephron by bradykinin The pathophysiology of anaphylaxis.

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P2860

Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

http://www.wikidata.org/entity/Q35233098

description

2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2004 թվականի հուլիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

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Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

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Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

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Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

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Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

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Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

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Journal of Clinical Investigation

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Involvement of chymase-mediated angiotensin II generation in blood pressure regulation.

@en

P2093

Ahsan Husain

http://www.w3.org/2001/XMLSchema#string

James A Angus

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Jan Michalicek

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John E Hunt

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Ke Liu

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Louis J Dell'Italia

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Michael P Feneley

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Ming Li

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Robert M Graham

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P2860

Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart

Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart

A novel vascular smooth muscle chymase is upregulated in hypertensive rats

Angiotensin II generation by mast cell alpha- and beta-chymases

Detection and partial characterization of a human mast cell carboxypeptidase

A despecialization step underlying evolution of a family of serine proteases.

Effects of angiotensin II generated by an angiotensin converting enzyme-independent pathway on left ventricular performance in the conscious baboon

Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases.

Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases.

Histochemical and ultrastructural modification of mucosal mast cell granules in parasitized mice lacking the beta-chymase, mouse mast cell protease-1.

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112-120

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10.1172/JCI20805

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1

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114

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437969

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