Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms.
about
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activityThe lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.Hematologic malignancies: newer strategies to counter the BCL-2 protein.Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein InteractionsCellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages.Gene-targeting pharmaceuticals for single-gene disorders.The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA.Molecular Mechanisms of Antisense Oligonucleotides.Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs.RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions.RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus.Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
P2860
Q28833550-C6B58033-89D7-468A-A90C-85982FE69E67Q33701404-B8E78B16-8B9E-45C8-AE5E-06F9A5015415Q34344380-8F012F3D-7D14-4566-ABB6-282F8C54C49FQ35979110-1D0347DD-92B7-4815-9DAC-86BFA31BDBCDQ36115825-6A8D2DA4-91E7-432A-B441-D324584F63E6Q36532644-B4E965DE-1ACE-44D3-AA6A-C1A88E10E878Q38300866-59EF909A-384E-426A-8B3D-F1B079D7E721Q38656342-AA740BBC-DDA1-4714-B060-9B0CC2E8BF2CQ40525237-4A0E266C-39F0-48CD-9785-BB514793BD02Q42293314-35B43E8C-4A9C-4272-BA99-407253169601Q47374105-2241A131-AD13-4F59-9EAF-6380F94C0258Q47786398-57D07077-FA1B-4A68-9111-713BBB5203ABQ52764171-56184E05-FB46-4728-A348-229892E47069Q57235283-58718375-8880-4B7F-BDE6-0C0F244F5D0D
P2860
Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@ast
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@en
type
label
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@ast
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@en
prefLabel
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@ast
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@en
P2860
P1433
P1476
Antisense oligonucleotides cap ...... nt and independent mechanisms.
@en
P2093
Stanley T Crooke
Timothy A Vickers
P2860
P304
P356
10.1371/JOURNAL.PONE.0108625
P407
P577
2014-10-09T00:00:00Z