UDP-glucuronosyltransferase (UGT) 1A9-overexpressing HeLa cells is an appropriate tool to delineate the kinetic interplay between breast cancer resistance protein (BRCP) and UGT and to rapidly identify the glucuronide substrates of BCRP.
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P1343
Interaction of Isoflavones with the BCRP/ABCG2 Drug TransporterRegioselective Glucuronidation of Diosmetin and Chrysoeriol by the Interplay of Glucuronidation and Transport in UGT1A9-Overexpressing HeLa CellsRevolving door action of breast cancer resistance protein (BCRP) facilitates or controls the efflux of flavone glucuronides from UGT1A9-overexpressing HeLa cells.Triple Recycling Processes Impact Systemic and Local Bioavailability of Orally Administered Flavonoids.Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP.A new strategy to rapidly evaluate kinetics of glucuronide efflux by breast cancer resistance protein (BCRP/ABCG2).Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides.Gender-dependent differences in uridine 5'-diphospho-glucuronosyltransferase have implications in metabolism and clearance of xenobiotics.Exploring concepts of in vitro time-dependent CYP inhibition assays.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathwaySGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats.Evaluation of UGT protein interactions in human hepatocytes: effect of siRNA down regulation of UGT1A9 and UGT2B7 on propofol glucuronidation in human hepatocytes.Challenges and Opportunities with Predicting in Vivo Phase II Metabolism via Glucuronidation from in Vitro Data.Chemical inhibition and stable knock-down of efflux transporters leads to reduced glucuronidation of wushanicaritin in UGT1A1-overexpressing HeLa cells: the role of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteinsHepatotoxicity Induced by Sophora flavescens and Hepatic Accumulation of Kurarinone, a Major Hepatotoxic Constituent of Sophora flavescens in Rats.Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3.Glucuronidation: driving factors and their impact on glucuronide dispositionEffect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats
P2860
Q26801110-E2B0C1CB-5EBA-4291-99B3-C7A1ADBD5CEBQ28553479-8012648F-FC82-48AA-8F67-3BFEE766AA3BQ33649076-2714265A-E3E7-47EE-867D-E07C0C388D8AQ35529130-D208603D-09AC-4207-A9E5-5FDC6285FE29Q36553783-1E4268B6-CFD1-4F7E-A347-D4F1DBAEFE73Q37636069-FC44EEBA-AB30-45E4-9491-EB3F049BCDDCQ37710997-FF1CDB0A-EA7A-444E-8E52-02793D3D7630Q38134859-7B8CF5A8-2A3E-4D43-9724-DF6EA67E1442Q38164432-C5217C29-3DD7-4981-849A-176456F52B8CQ38207943-9A4A6F70-DC21-4159-97F6-0F02B245FA06Q38797489-D88793D6-E941-4C5D-B601-51B6248FEF7CQ38812309-91594033-F09C-4B31-9AB6-4C3F3D2996D6Q40766662-9F40091C-F042-4E9D-AE6E-02BA1CFF1E80Q45345117-3E42FD0A-1AA1-4109-8784-87A2F1C314D8Q47215160-B8789989-FFBE-47E7-93C0-B543CB11F89AQ48130339-75892C79-48BB-4A01-A8EF-AA8356F3676CQ52863132-830AEF6F-B7EF-420D-8977-B9E0AA5B4364Q56030213-890087E1-3072-4DEA-AC0D-3EF215ED74CFQ57113952-D3FF257F-451E-4014-A315-6EACBA7AEA1F
P2860
UDP-glucuronosyltransferase (UGT) 1A9-overexpressing HeLa cells is an appropriate tool to delineate the kinetic interplay between breast cancer resistance protein (BRCP) and UGT and to rapidly identify the glucuronide substrates of BCRP.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@ast
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@en
type
label
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@ast
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@en
prefLabel
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@ast
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@en
P2093
P2860
P356
P1476
UDP-glucuronosyltransferase (U ...... lucuronide substrates of BCRP.
@en
P2093
P2860
P304
P356
10.1124/DMD.111.041467
P4510
P577
2011-11-09T00:00:00Z