A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.
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Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulatorInduction of cyclin D1 by simian virus 40 small tumor antigenSimian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor.Ligand binding to the androgen receptor induces conformational changes that regulate phosphatase interactionsEffects of simian virus 40 large and small tumor antigens on mammalian target of rapamycin signaling: small tumor antigen mediates hypophosphorylation of eIF4E-binding protein 1 late in infection.Transactivation of murine cyclin A by polyomavirus large and small T antigens.Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts.Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cellsT antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisSmall tumor antigen of polyomaviruses: role in viral life cycle and cell transformationCellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Simian virus 40 large T antigen and two independent T-antigen segments sensitize cells to apoptosis following genotoxic damagep27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation.Role of SV40 ST antigen in the persistent infection of mesothelial cells.Simian virus 40 T antigens and J domains: analysis of Hsp40 cochaperone functions in Escherichia coli.The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.SV40 reporter viruses.PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigenHuman mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity.Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function.The simian virus 40 small-t and large-T antigens jointly regulate cell cycle reentry in human fibroblasts.Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A.Polyomavirus T antigens: molecular chaperones for multiprotein complexes.Cell cycle progression in monkey cells expressing simian virus 40 small t antigen from adenovirus vectors.pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppressionBinding of polyomavirus small T antigen to protein phosphatase 2A is required for elimination of p27 and support of S-phase induction in concert with large T antigen.Induction of p53-independent apoptosis by simian virus 40 small t antigen.Overexpression of simian virus 40 small-T antigen blocks centrosome function and mitotic progression in human fibroblasts.Effect on polyomavirus T-antigen function of mutations in a conserved leucine-rich segment of the DnaJ domainThe minimum replication origin of merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication.Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E.Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain.Dephosphorylation of JC virus agnoprotein by protein phosphatase 2A: inhibition by small t antigen.Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cellsBK virus as a cofactor in the etiology of prostate cancer in its early stages.
P2860
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P2860
A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
A novel simian virus 40 early- ...... ll-t antigen-dependent assays.
@ast
A novel simian virus 40 early- ...... ll-t antigen-dependent assays.
@en
type
label
A novel simian virus 40 early- ...... ll-t antigen-dependent assays.
@ast
A novel simian virus 40 early- ...... ll-t antigen-dependent assays.
@en
prefLabel
A novel simian virus 40 early- ...... ll-t antigen-dependent assays.
@ast
A novel simian virus 40 early- ...... ll-t antigen-dependent assays.
@en
P2093
P2860
P1433
P1476
A novel simian virus 40 early- ...... all-t antigen-dependent assays
@en
P2093
B Henglein
B Thimmapaya
S Sathyamangalam
P2860
P304
P407
P577
1996-10-01T00:00:00Z