Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
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Peptide-Induced Amyloid-Like Conformational Transitions in ProteinsMolecular Details of Olfactomedin Domains Provide Pathway to Structure-Function StudiesThe glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequenceLigands for glaucoma-associated myocilin discovered by a generic binding assayABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells.Structural basis for misfolding in myocilin-associated glaucoma.Mutated myocilin and heterozygous Sod2 deficiency act synergistically in a mouse model of open-angle glaucoma.Novel and known MYOC exon 3 mutations in an admixed Peruvian primary open-angle glaucoma populationGlucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism.The glaucoma-associated olfactomedin domain of myocilin is a novel calcium binding protein.A Novel Luciferase Assay For Sensitively Monitoring Myocilin Variants in Cell Culture.Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.A conservative mutant of a proteolytic fragment produced during fibril formation enhances fibrillogenesisExploiting the interaction between Grp94 and aggregated myocilin to treat glaucomaAmyloidogenic peptide homologous to fragment 129-148 of human myocilin.Cartilage acidic protein 1, a new member of the beta-propeller protein family with amyloid propensity.Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.New direction for glaucoma therapeutics: focus on the olfactomedin domain of myocilin.
P2860
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P2860
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@ast
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@en
type
label
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@ast
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@en
prefLabel
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@ast
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@en
P2093
P2860
P1476
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.
@en
P2093
Christopher W Perry
Douglas Vollrath
Ingeborg Schmidt-Krey
Katherine C Turnage
Laura Y Kim
Raquel L Lieberman
Rong Zhang
Susan D Orwig
P2860
P304
P356
10.1016/J.JMB.2011.12.016
P407
P577
2011-12-13T00:00:00Z