Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-kappaB site.
about
Interleukin-15 biology and its therapeutic implications in cancerRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityThe HTLV-1 Tax protein binding domain of cyclin-dependent kinase 4 (CDK4) includes the regulatory PSTAIRE helixElevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-kappaB activation.Oncogenes and RNA splicing of human tumor virusesLife, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformationSurvival adjustment of mature dendritic cells by IL-15.Treatment of HTLV-I-Associated Myelopathy / Tropical Spastic Paraparesis: Towards Rational Targeted TherapyHigh expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic diseaseThe frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesisPathological roles of interleukin-15 in adult T-cell leukemia.IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cellsPersistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.Viral activation of interleukin-15 (IL-15): characterization of a virus-inducible element in the IL-15 promoter region.IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients.Aberrant activation of the interleukin-2 autocrine loop through the nuclear factor of activated T cells by nonleukemogenic human T-cell leukemia virus type 2 but not by leukemogenic type 1 virusFibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31.Molecular pathways in virus-induced cytokine production.IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.Molecular mechanisms of cellular transformation by HTLV-1 Tax.Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemiaCP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSPThe contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseasesInhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I-associated neurologic disease.IL-15 deficient tax mice reveal a role for IL-1α in tumor immunityTCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax.Human T-cell leukemia virus type I and adult T-cell leukemia.T cell interleukin-15 surface expression in chimpanzees infected with human immunodeficiency virus.Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease.Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling.Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax.Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes.Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis.Wild-type p53-mediated down-modulation of interleukin 15 and interleukin 15 receptors in human rhabdomyosarcoma cellsPorcine reproductive and respiratory syndrome virus induces interleukin-15 through the NF-κB signaling pathwayHTLV-1 drives vigorous clonal expansion of infected CD8(+) T cells in natural infection.Cotranscriptional Chromatin Remodeling by Small RNA Species: An HTLV-1 PerspectiveHumoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individualsInduction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism
P2860
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P2860
Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-kappaB site.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@ast
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@en
type
label
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@ast
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@en
prefLabel
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@ast
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@en
P2093
P2860
P356
P1476
Human T cell lymphotropic viru ...... ion through an NF-kappaB site.
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.5.2452
P407
P577
1998-03-01T00:00:00Z