Biochemical mechanisms for translational regulation in synaptic plasticity.
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Pharmacological brake-release of mRNA translation enhances cognitive memoryDisrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophreniaNMDA receptor activation dephosphorylates AMPA receptor glutamate receptor 1 subunits at threonine 840FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autismmTOR signaling: at the crossroads of plasticity, memory and diseaseRheb and mTOR regulate neuronal polarity through Rap1BThreats to the mind: aging, amyloid, and hypertensionMammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain FunctionRibosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to FunctionCharacterizing autism spectrum disorders by key biochemical pathways.The function of RNA-binding proteins at the synapse: implications for neurodegenerationSystematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stabilityDegradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activationCPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNAExpression of the core exon-junction complex factor eukaryotic initiation factor 4A3 is increased during spatial exploration and striatally-mediated learningBrain-derived neurotrophic factor enhances the basal rate of protein synthesis by increasing active eukaryotic elongation factor 2 levels and promoting translation elongation in cortical neuronsSynaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticityLithium administration to preadolescent rats causes long-lasting increases in anxiety-like behavior and has molecular consequences.Conditional knockout of tumor overexpressed gene in mouse neurons affects RNA granule assembly, granule translation, LTP and short term habituation.Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage.Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behaviorProtein synthesis in distal axons is not required for growth cone responses to guidance cuesSuppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits.eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory.Limited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer's disease.Local translation in primary afferent fibers regulates nociceptionStress-dependent coordination of transcriptome and translatome in yeastAssessment of the role of MAP kinase in mediating activity-dependent transcriptional activation of the immediate early gene Arc/Arg3.1 in the dentate gyrus in vivo.Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease.Endoplasmic reticulum stress and inflammation in the central nervous systemFrom mTOR to cognition: molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis.Intracellular calcium and calmodulin link brain-derived neurotrophic factor to p70S6 kinase phosphorylation and dendritic protein synthesis.Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizuresThe A-current modulates learning via NMDA receptors containing the NR2B subunitPrion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTORAxonal cap-dependent translation regulates presynaptic p35.A simple role for BDNF in learning and memory?Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.
P2860
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P2860
Biochemical mechanisms for translational regulation in synaptic plasticity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Biochemical mechanisms for translational regulation in synaptic plasticity.
@ast
Biochemical mechanisms for translational regulation in synaptic plasticity.
@en
type
label
Biochemical mechanisms for translational regulation in synaptic plasticity.
@ast
Biochemical mechanisms for translational regulation in synaptic plasticity.
@en
prefLabel
Biochemical mechanisms for translational regulation in synaptic plasticity.
@ast
Biochemical mechanisms for translational regulation in synaptic plasticity.
@en
P2860
P356
P1476
Biochemical mechanisms for translational regulation in synaptic plasticity.
@en
P2093
Eric Klann
P2860
P2888
P304
P356
10.1038/NRN1557
P407
P50
P577
2004-12-01T00:00:00Z