about
Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substratesThe chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genomeNSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen SpeciesOcular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic dispositionProcarcinogens - Determination and Evaluation by Yeast-Based Biosensor Transformed with Plasmids Incorporating RAD54 Reporter Construct and Cytochrome P450 GenesStructural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Cytochrome P450 CYP2 genes in the common cormorant: Evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expressionMultiple cytochrome P-450 genes are concomitantly regulated by vitamin A under steady-state conditions and by retinoic acid during hepatic first-pass metabolism.Bioelectronic delivery of electrons to cytochrome P450 enzymesUltrastructural changes, increased oxidative stress, inflammation, and altered cardiac hypertrophic gene expressions in heart tissues of rats exposed to incense smoke.Deleterious effects of incense smoke exposure on kidney function and architecture in male albino rats.In Silico Predictions of Drug - Drug Interactions Caused by CYP1A2, 2C9 and 3A4 Inhibition - a Comparative Study of Virtual Screening Performance.Metabolic toxicity screening using electrochemiluminescence arrays coupled with enzyme-DNA biocolloid reactors and liquid chromatography-mass spectrometry.Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeastComparison of DNA-Reactive Metabolites from Nitrosamine and Styrene Using Voltammetric DNA/Microsomes Sensors.Role of nutrition in preventing cancerActivation of aflatoxin B1 by expression of human CYP1A2 polymorphisms in Saccharomyces cerevisiae.Structure-based methods for the prediction of drug metabolism.Control of electrochemical and ferryloxy formation kinetics of cyt P450s in polyion films by heme iron spin state and secondary structureState-of-the-Art Metabolic Toxicity Screening and Pathway Evaluation.Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines.A suite of activity-based probes for human cytochrome P450 enzymes.A case-control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk in Cantonese.Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.Hormonal regulation of CYP1A expression.Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices.Cytochrome P450-Mediated Phytoremediation using Transgenic Plants: A Need for Engineered Cytochrome P450 Enzymes.Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs.CYP1A1 I462V polymorphism is associated with reduced genotoxicity in yeast despite positive association with increased cancer risk.Non-cytochrome P450-mediated bioactivation and its toxicological relevance.Underlying role of mitochondrial mutagenesis in the pathogenesis of a disease and current approaches for translational research.Garlic oil attenuated nitrosodiethylamine-induced hepatocarcinogenesis by modulating the metabolic activation and detoxification enzymes.MODULATION OF CARCINOGEN-METABOLIZING ENZYME BY MADINAH MINT (Mentha spp) IN RAT LIVERCCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the develTranscriptional regulation of chicken cytochrome P450 2D49 basal expression by CCAAT/enhancer-binding protein α and hepatocyte nuclear factor 4α.Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices.Modulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice.The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.Effect of aflatoxin B1 on nuclear receptors PXR, CAR, and AhR and their target cytochromes P450 mRNA expression in primary cultures of human hepatocytes.
P2860
Q24316102-5CD38BF8-803D-48F6-BEB1-63FBBCCC15C0Q24605756-1438324F-C17D-435B-85D7-4A4D7FAEF7D8Q26784322-48190862-1A08-45EA-9C5F-E864CBFE05EBQ26851574-3845F52B-D55D-4586-B96D-FEFEEAB0A898Q28555181-3C31C2E6-E71D-491E-B9E3-396C20155077Q30396630-AC6A62E5-3C99-4C83-A40D-4A03CFB8FB18Q30992845-78D49112-2C1E-45BF-9607-42D0723D3F86Q34518046-F181A693-80F3-4D24-A31B-069930AF5B3CQ35082373-6C4A4F01-5D88-4DB8-8203-93C465C107FEQ35562332-571539FF-503C-4684-BADF-6214D21FBC1AQ36018170-762F615D-421F-4830-87AA-18AE2D07D7C3Q36094897-66715242-EC9D-44B6-A245-ED54236D5A4FQ36102391-70C66D04-8FD9-4D8E-B448-868DE3BA8119Q36103717-BEB49B3F-B439-4D20-8F40-69D25D468005Q36340168-7FA5710F-1CBB-4B7A-A925-4FE047C41F2CQ36440322-A11524C9-1057-4E6A-8C82-908C79C39D61Q36450003-1C7E4EED-0FCE-42E4-BD3A-8AF69F94EFA6Q36543100-72A724B6-AD14-4E2F-BCE9-7B01316FC7E3Q36620573-22D31825-9C09-4BC2-98B7-BC7B1FFBD42BQ36887497-B3E4CC06-B1E3-46C3-B3FE-F4994D81EEA4Q37026167-7E5F8FC4-6CA3-445F-A4E2-F8A715134405Q37331285-BEFDA2DA-AA1C-4281-8A1C-92CBA78F5039Q37472132-60C1A35E-6AC9-466F-8DE7-E64CACCEA950Q37514128-A049D04C-E495-44C2-B58B-E8DC96F16289Q37559609-1499D072-C02A-441F-870D-D39F0FF6842CQ37975545-3D0C5651-11EF-47AA-A02C-24820DF801EEQ38022331-8A154C91-2091-4CCE-8AEB-E0C98789537EQ38258353-07D006DE-FEF7-41E4-AB24-0C5E8988EB41Q38675826-19D8E1EC-7A81-4EA6-9918-053E30A80543Q38914395-EDBB6CA0-3D99-46A9-86DE-9F48FA0B301DQ38929936-2AB7F9F8-AE4B-4605-BAEA-31AD3C1DC15EQ39000027-3D850837-BA16-4134-B237-4D6BEA65A2C9Q41160662-A697B65D-42CC-4CD4-AEBB-FF982C24851BQ41662497-28675A34-6F94-4496-B137-451A65120981Q42140049-2A8DE0B9-02F4-4F88-8A0B-F46FA9AF6400Q42452361-AF03C0A1-8F06-41D2-A07B-278ACAF5B6FEQ42697848-D8A4AF5E-3097-4717-8AE4-02BB9E305435Q42701599-D0FAA1DF-88C7-4D1A-8B48-0D6269011F60Q42717837-1A3D0A26-AFEB-49BE-9445-D7E4D8BC1E76Q42726093-8FCC14AB-8289-4B32-A3A5-9D5E34F8AC30
P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Cytochromes P450 in the bioactivation of chemicals.
@ast
Cytochromes P450 in the bioactivation of chemicals.
@en
type
label
Cytochromes P450 in the bioactivation of chemicals.
@ast
Cytochromes P450 in the bioactivation of chemicals.
@en
prefLabel
Cytochromes P450 in the bioactivation of chemicals.
@ast
Cytochromes P450 in the bioactivation of chemicals.
@en
P356
P1476
Cytochromes P450 in the bioactivation of chemicals.
@en
P2093
Costas Ioannides
David F V Lewis
P304
P356
10.2174/1568026043387188
P577
2004-01-01T00:00:00Z