CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling.
about
Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activitySerum biomarker profile associated with high bone turnover and BMD in postmenopausal women.Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarinBeta sheet 2-alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners.Assessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format.Application of MassSQUIRM for quantitative measurements of lysine demethylase activity.Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations.MassSQUIRM: An assay for quantitative measurement of lysine demethylase activityUnusual regioselectivity and active site topology of human cytochrome P450 2J2Global analysis of protein-protein interactions reveals multiple CYP2E1-reductase complexes.Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes.Cooperative effects for CYP2E1 differ between styrene and its metabolites.CYP2E1 substrate inhibition. Mechanistic interpretation through an effector site for monocyclic compoundsDevelopment and evaluation of a structural model for SF1B helicase Dda.Murburn Concept: A Molecular Explanation for Hormetic and Idiosyncratic Dose Responses.
P2860
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P2860
CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
CYP2E1 active site residues in ...... abeling and homology modeling.
@ast
CYP2E1 active site residues in ...... abeling and homology modeling.
@en
type
label
CYP2E1 active site residues in ...... abeling and homology modeling.
@ast
CYP2E1 active site residues in ...... abeling and homology modeling.
@en
prefLabel
CYP2E1 active site residues in ...... abeling and homology modeling.
@ast
CYP2E1 active site residues in ...... abeling and homology modeling.
@en
P2093
P2860
P1476
CYP2E1 active site residues in ...... abeling and homology modeling.
@en
P2093
Alan J Tackett
Anna Radominska-Pandya
Arvind P Jamakhandi
Grover P Miller
Samuel L Collom
P2860
P356
10.1016/J.ABB.2006.10.028
P407
P577
2006-11-02T00:00:00Z