Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion. - sprookjes - yvandenbroek - TriplyDB

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

http://www.wikidata.org/entity/Q36121784

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International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system Toward a mechanism-based in vitro safety test for pertussis toxin Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5 Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes Modulation of gene expression by 3-iodothyronamine: genetic evidence for a lipolytic pattern An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow G protein coupled receptors in embryonic stem cells: a role for Gs-alpha signaling.A β-peptide agonist of the GLP-1 receptor, a class B GPCR.Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells.A comparative analysis of human and mouse islet G-protein coupled receptor expression.Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells.Local protease signaling contributes to neural tube closure in the mouse embryo Torpor: The Rise and Fall of 3-Monoiodothyronamine from Brain to Gut-From Gut to Brain?RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo Effects of acute microinjections of the thyroid hormone derivative 3-iodothyronamine to the preoptic region of adult male rats on sleep, thermoregulation and motor activity.Structure, biological functions and applications of the AB5 toxins.Evidence for the gut microbiota short-chain fatty acids as key pathophysiological molecules improving diabetes.Repurposing cAMP-modulating medications to promote β-cell replication.Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2)Incretin-like effects of small molecule trace amine-associated receptor 1 agonists.CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function.Augmented glucose-induced insulin release in mice lacking G(o2), but not G(o1) or G(i) proteins Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications.Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation.Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis PKA Enhances the Acute Insulin Response Leading to the Restoration of Glucose Control.GPR43 Potentiates β-Cell Function in Obesity.ApoB-100-containing lipoproteins are major carriers of 3-iodothyronamine in circulation.Negative association of acetate with visceral adipose tissue and insulin levels.The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites 3-Iodothyronamine: a modulator of the hypothalamus-pancreas-thyroid axes in mice.Understanding the Healthy Thyroid State in 2015.

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Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

http://www.wikidata.org/entity/Q36121784

description

2007 nî lūn-bûn

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name

Probing cell type-specific fun ...... gulators of insulin secretion.

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Probing cell type-specific fun ...... gulators of insulin secretion.

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Probing cell type-specific fun ...... gulators of insulin secretion.

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Probing cell type-specific fun ...... gulators of insulin secretion.

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Probing cell type-specific fun ...... gulators of insulin secretion.

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Probing cell type-specific fun ...... gulators of insulin secretion.

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Journal of Clinical Investigation

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Probing cell type-specific fun ...... egulators of insulin secretion

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Hiroshi Kataoka

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Jean B Regard

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Liya Yin

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Matthias Hebrok

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Shaun R Coughlin

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Thomas S Scanlan

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Yao-Wu Zheng

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P2860

Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

Trace amines: identification of a family of mammalian G protein-coupled receptors

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

The G protein-coupled receptor repertoires of human and mouse

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

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4034-4043

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10.1172/JCI32994

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17992256

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G protein-coupled receptor

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2066199

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