Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts?
about
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleTargeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulatorTwists in views on RB functions in cellular signaling, metabolism and stem cellsRB1: a prototype tumor suppressor and an enigmaUnderstanding pRb: toward the necessary development of targeted treatments for retinoblastomaA Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus PolymeraseA bistable circuit involving SCARECROW-RETINOBLASTOMA integrates cues to inform asymmetric stem cell division.RETINOBLASTOMA-RELATED protein stimulates cell differentiation in the Arabidopsis root meristem by interacting with cytokinin signaling.Loss of the mammalian DREAM complex deregulates chondrocyte proliferationA mitosis block links active cell cycle with human epidermal differentiation and results in endoreplication.p107 in the public eye: an Rb understudy and more.Conformational dissection of a viral intrinsically disordered domain involved in cellular transformation.Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model.Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97.Differentiation resistance through altered retinoblastoma protein function in acute lymphoblastic leukemia: in silico modeling of the deregulations in the G1/S restriction point pathway.Evidence for autoregulation and cell signaling pathway regulation from genome-wide binding of the Drosophila retinoblastoma protein.Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in CancerRegulation of the retinoblastoma proteins by the human herpesviruses.Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme.ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.Key elements of the retinoblastoma tumor suppressor pathway in Volvox carteri.Regulation of transcription and chromatin structure by pRB: here, there and everywhere.Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function.The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations.The potential role of PD0332991 (Palbociclib) in the treatment of multiple myeloma.Roles of pRB in the Regulation of Nucleosome and Chromatin Structures.Dephosphorylation of threonine-821 of the retinoblastoma tumor suppressor protein (Rb) is required for apoptosis induced by UV and Cdk inhibition.A cancer derived mutation in the retinoblastoma gene with a distinct defect for LXCXE dependent interactions.Folding of a cyclin box: linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor AB pocket domainPhosphorylation puts the pRb tumor suppressor into shape.The retinoblastoma protein: multitasking to suppress tumorigenesis.MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter.LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence.The retinoblastoma protein and PML collaborate to organize heterochromatin and silence E2F-responsive genes during senescence.Discovery and Pharmacological Characterisation of a Novel Series of Highly Selective Inhibitors of Cyclin-Dependent Kinases 4 and 6 as Anticancer Agents.Modeling human osteosarcoma in mice through 3AB-OS cancer stem cell xenografts.A gender-specific retinoblastoma-related protein in Volvox carteri implies a role for the retinoblastoma protein family in sexual development.
P2860
Q21203547-4DF1B871-A80C-4208-99FA-B0D0209BD3FEQ24296551-F91195F0-9DD8-4BF7-BF9A-7ADF2E1E6D0EQ24297641-0FA34B60-9408-4DBB-859C-664953F57028Q26828495-F64A1E04-7B40-46BF-92EB-5DF046B64525Q26866393-38F0ADC0-1818-451C-B5E2-7F7E355B7457Q27011911-9B3F651A-AB0A-4976-8243-0E1DD3D52384Q27486419-75222ED5-52A3-40F4-A3E1-1EF917AB203FQ30528448-A6C5B097-26B6-423F-9F50-073CE3F99157Q33357216-DC4DEC28-9B83-4555-840F-6F46EF7DFE3EQ33743583-F7BD5ECF-E788-4393-B9C2-1FCD91F3E3A3Q33781053-4EEC1ABD-617D-4518-AD18-CF8925A9B64FQ33818607-CECADBE3-5E32-4806-880D-FB70559DACF2Q35004677-A927900B-36A3-459B-9816-1F9850FA51B6Q35110344-7EC3FF1B-7804-43B0-A43A-1C6CBCDFFC27Q35925834-E86E01D2-486D-4B7E-9A93-32221A107460Q35942281-4F7444A6-9696-420E-A70B-6FBAAFBC876DQ36358549-B0BE7570-9534-45BA-B52E-EDFE3AFD2A56Q36538573-0A062DC4-6E39-4078-89AB-1FEB03734B8FQ36747304-E2D3947C-54D1-4594-9B05-DACF1162134CQ36796453-DBE54A39-D41B-43BF-B16E-43B81E117732Q37085853-76E79A61-BE2E-4F20-8643-CAF938091DEBQ37122885-9BAC878B-D6D6-4F58-84B6-31CA43114E2DQ37122929-D0CA6230-CF61-4CFB-8AB4-4E92D090E1B3Q37416373-46D44DB0-DBD9-4C32-9A39-3DFD50B656FDQ38034873-6DA59598-0EC0-44FA-85E0-4945A37B33D2Q38103250-6ADEBADA-6728-407D-87F7-92DCB559F27BQ38178032-8CC9A8D6-8A54-43EC-99AA-1C74853C07A3Q38286180-ECA6B294-233A-44FD-92F1-5B78AC9643D4Q39094351-092AC54B-F334-44CD-AF07-A49EF94A073CQ39297101-574E766B-0C1E-4B5B-B551-4B288FAA6AF3Q40197153-7271603F-FBBB-4B63-8877-460038331CA2Q41468886-2899960E-0970-4F0C-85FA-B37DDFFFCD00Q41861650-B7E69760-E2DD-4CB3-90DE-FDA081527AD7Q42104939-17F17EFA-C6C0-4B8D-A212-5568EE58CA7DQ42120621-10533A0F-15E0-4824-8B83-54F6A4CC2F83Q42141813-677D73FD-8B69-43FF-877C-3FA23EF3A74CQ44803954-94F40E83-084A-4D72-B3B9-59F2B4E7658CQ47963513-437E6358-C24D-4931-BAAF-72E474CF36C8Q50575582-745B19F0-0DB0-4C77-96D4-2CF6CD0CE3D6Q50621071-3B1D8E01-1F9E-401A-942A-AE6386888162
P2860
Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts?
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Structure-function analysis of ...... the whole a sum of its parts?
@ast
Structure-function analysis of ...... the whole a sum of its parts?
@en
type
label
Structure-function analysis of ...... the whole a sum of its parts?
@ast
Structure-function analysis of ...... the whole a sum of its parts?
@en
prefLabel
Structure-function analysis of ...... the whole a sum of its parts?
@ast
Structure-function analysis of ...... the whole a sum of its parts?
@en
P2860
P356
P1433
P1476
Structure-function analysis of ...... the whole a sum of its parts?
@en
P2093
Frederick A Dick
P2860
P2888
P356
10.1186/1747-1028-2-26
P577
2007-09-13T00:00:00Z
P5875
P6179
1014067253