Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.
about
Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signallingOrganotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells.Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth.Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesisPancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner.Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.New ideas connecting the cell cycle and pancreatic endocrine-lineage specification.Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.FUCCI tracking shows cell-cycle-dependent Neurog3 variation in pancreatic progenitors.In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.Cellular and molecular mechanisms coordinating pancreas development.Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis.Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesisDefining Lineage Potential and Fate Behavior of Precursors during Pancreas Development
P2860
Q30811680-9CFE42AA-7283-41F9-99B9-0E61DC5A6E67Q36293831-E2D52C70-5FEE-4F2F-BD15-CA95910501F5Q41542262-1A7ACEAB-3304-4B7A-BC70-84566C74331AQ41689788-8CC28A56-8C88-408A-89ED-2C062AA265B2Q41701234-3296565F-54F0-43E3-9B88-7EA51982E852Q41963629-FABDD7B7-8777-4FA7-B491-3E54BDEAEFBCQ42564616-F543E39D-4A30-44F9-BD94-196818711527Q44072525-482DFFF0-3EE9-4812-8ECB-85D990C8550FQ46629073-FE4F0E6B-B869-42AF-B032-D708DA0FF33BQ47304853-8C77566B-FA1B-41B9-B086-C17F1FFA94E5Q47554062-48E01BF5-6026-46EB-BEE5-0534B8E0B4AAQ47617045-6EE2CC51-C1DC-4D72-B8B0-8CFE70EB35B3Q48235399-CA22B7A3-F326-452F-8599-B00EBEE6455CQ50058808-5DFE5AFC-ECC9-42BB-A5D9-2A22CEABC9E2Q55104265-DAB1BD47-1697-442A-BC86-F28948931DCEQ58721561-F25CA12F-EB6C-430E-8D78-3CD69BB56199Q58799211-181B489A-BCAA-4FAC-974D-8BAF4E7FF2F6
P2860
Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Feedback control of growth, di ...... in an epithelial plexus niche.
@ast
Feedback control of growth, di ...... in an epithelial plexus niche.
@en
type
label
Feedback control of growth, di ...... in an epithelial plexus niche.
@ast
Feedback control of growth, di ...... in an epithelial plexus niche.
@en
prefLabel
Feedback control of growth, di ...... in an epithelial plexus niche.
@ast
Feedback control of growth, di ...... in an epithelial plexus niche.
@en
P2860
P356
P1433
P1476
Feedback control of growth, di ...... in an epithelial plexus niche
@en
P2093
Christopher V E Wright
Eric D Bankaitis
P2860
P304
P356
10.1101/GAD.267914.115
P577
2015-10-01T00:00:00Z