Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.
about
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitFunctions of the major tyrosine phosphorylation site of the PDGF receptor beta subunitThe 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase SypExpression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression systemEvidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase.Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesInsulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivoPhosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1Growth factor-induced activation of a kinase activity which causes regulatory phosphorylation of p42/microtubule-associated protein kinaseA 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts.Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetateTyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblastsPhosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinaseRegulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycleThe GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activityTyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectivelyIdentification of a 42-kilodalton phosphotyrosyl protein as a serine(threonine) protein kinase by renaturation.Mitogenic signaling pathways of growth factors can be distinguished by the involvement of pertussis toxin-sensitive guanosine triphosphate-binding protein and of protein kinase C.Extracellular signal-regulated kinases: ERKs in progress.Related proteins are phosphorylated at tyrosine in response to mitogenic stimuli and at meiosisA 41-kilodalton protein is a potential substrate for the p210bcr-abl protein-tyrosine kinase in chronic myelogenous leukemia cells.Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifsPhorbol ester stimulates a protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product.Extracellular signal-regulated kinases 2 autophosphorylates on a subset of peptides phosphorylated in intact cells in response to insulin and nerve growth factor: analysis by peptide mapping.The ERK 1 and 2 pathway in the nervous system: from basic aspects to possible clinical applications in pain and visceral dysfunction.Human microvascular endothelial cells express receptors for platelet-derived growth factor.Dual-specificity phosphatases 2: surprising positive effect at the molecular level and a potential biomarker of diseases.Identification of a putative Syp substrate, the PDGF beta receptor.Identification of a mouse homolog of the human BTEB2 transcription factor as a beta-catenin-independent Wnt-1-responsive gene.Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway.Temperature-dependent tyrosine phosphorylation of microtubule-associated protein kinase in epidermal growth factor-stimulated human fibroblasts.Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways.The aetiology of clubbing and hypertrophic osteoarthropathy.Activation of Raf-1 during experimental gastric ulcer healing is Ras-mediated and protein kinase C-independentCross-talk between phorbol ester-mediated signaling and tyrosine kinase proto-oncogenes. I. Activation of protein kinase C stimulates tyrosine phosphorylation and activation of ErbB2 and ErbB3.Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts.Activation of mitogen-activated protein kinase couples neurotensin receptor stimulation to induction of the primary response gene Krox-24.Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells.
P2860
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P2860
Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@ast
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@en
type
label
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@ast
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@en
prefLabel
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@ast
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@en
P2860
P356
P1476
Protein kinase C mediates plat ...... rosine phosphorylation of p42.
@en
P2093
A Kazlauskas
J A Cooper
P2860
P304
P356
10.1083/JCB.106.4.1395
P407
P577
1988-04-01T00:00:00Z