TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. - sprookjes - yvandenbroek - TriplyDB

TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.

TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.

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Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical Appraisal Stem cell technology in breast cancer: current status and potential applications Remodeling Components of the Tumor Microenvironment to Enhance Cancer Therapy The Promise of Preventive Cancer Vaccines Insidious changes in stromal matrix fuel cancer progression Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)Exploring the tumor microenvironment with nanoparticles Intravital Microscopy Imaging Approaches for Image-Guided Drug Delivery Systems Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia.Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers.Netrin-4 promotes mural cell adhesion and recruitment to endothelial cells.Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model.Polyclonal rabbit anti-human ovarian cancer globulins inhibit tumor growth through apoptosis involving the caspase signaling.The roles of TGFβ in the tumour microenvironment.Pirfenidone normalizes the tumor microenvironment to improve chemotherapy The role of mechanical forces in tumor growth and therapy Fibroblast heterogeneity in the cancer wound.Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan Anticancer drug-loaded multifunctional nanoparticles to enhance the chemotherapeutic efficacy in lung cancer metastasis Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and function The lung metastatic niche.The role of cytokines in breast cancer development and progression Targeting the tumor microenvironment to enhance antitumor immune responses Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy.Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase.Identification of stromal ColXα1 and tumor-infiltrating lymphocytes as putative predictive markers of neoadjuvant therapy in estrogen receptor-positive/HER2-positive breast cancer Design considerations for nanotherapeutics in oncology.Transforming growth factor-β: guardian of catabolic metabolism in carcinoma-associated fibroblasts.Alk5 inhibition increases delivery of macromolecular and protein-bound contrast agents to tumors.Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer.Carcinoma-associated fibroblasts are a promising therapeutic target.Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.Combining two strategies to improve perfusion and drug delivery in solid tumors.Photoswitchable nanoparticles for in vivo cancer chemotherapy Nanoparticles and their applications in cell and molecular biology.Image-Guided Radiotherapy Targets Macromolecules through Altering the Tumor Microenvironment.Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer Hyaluronan-Derived Swelling of Solid Tumors, the Contribution of Collagen and Cancer Cells, and Implications for Cancer Therapy.

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TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.

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TGF-β blockade improves the di ...... normalizing the tumor stroma.

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Proceedings of the National Academy of Sciences of the United States of America

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TGF-β blockade improves the di ...... y normalizing the tumor stroma

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Benjamin Diop-Frimpong

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Jieqiong Liu

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Lei Xu

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Marek Ancukiewicz

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Rakesh K Jain

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Shan Liao

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Shom Goel

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Wei Chen

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Yves Boucher

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P2860

Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

Molecular regulation of vessel maturation

Normalization of the vasculature for treatment of cancer and other diseases.

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors.

TGF-beta biology in mammary development and breast cancer.

Stromal regulation of vessel stability by MMP14 and TGFbeta.

Delivery of molecular and cellular medicine to solid tumors.

Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors.

TGF-beta blockade controls ascites by preventing abnormalization of lymphatic vessels in orthotopic human ovarian carcinoma models.

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Kamila Naxerova

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