Bmi1 is required for regeneration of the exocrine pancreas in mice
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Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tractGenetically engineered mouse models of pancreatic adenocarcinomaIslet biology, the CDKN2A/B locus and type 2 diabetes risk.Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro.Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.Regeneration and repair of the exocrine pancreas.Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiationβ1 integrin is a crucial regulator of pancreatic β-cell expansion.Epigenetic modifications and long noncoding RNAs influence pancreas development and function.Acinar cell reprogramming: a clinically important target in pancreatic disease.Lineage specific expression of Polycomb Group Proteins in human embryonic stem cells in vitro.A CCR2+ myeloid cell niche required for pancreatic β cell growth.Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells.p21(WAF1) (/Cip1) limits senescence and acinar-to-ductal metaplasia formation during pancreatitis.Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation.
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Bmi1 is required for regeneration of the exocrine pancreas in mice
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
Bmi1 is required for regeneration of the exocrine pancreas in mice
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Bmi1 is required for regeneration of the exocrine pancreas in mice
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type
label
Bmi1 is required for regeneration of the exocrine pancreas in mice
@ast
Bmi1 is required for regeneration of the exocrine pancreas in mice
@en
prefLabel
Bmi1 is required for regeneration of the exocrine pancreas in mice
@ast
Bmi1 is required for regeneration of the exocrine pancreas in mice
@en
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Bmi1 is required for regeneration of the exocrine pancreas in mice
@en
P2093
Akihisa Fukuda
John P Morris
Matthias Hebrok
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821-831.e2
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10.1053/J.GASTRO.2012.05.009
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2012-05-17T00:00:00Z