CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6 - sprookjes - yvandenbroek - TriplyDB

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

http://www.wikidata.org/entity/Q36581691

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Dynamic regulation of the COP9 signalosome in response to DNA damage ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development The COP9 signalosome subunit 6 (CSN6): a potential oncogene CSN6 drives carcinogenesis by positively regulating Myc stability.The COP9 signalosome and vascular function: intriguing possibilities?CSN6 deregulation impairs genome integrity in a COP1-dependent pathway Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis.COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer.CSN6 positively regulates c-Jun in a MEKK1-dependent manner.Akt destabilizes p57 (Kip2) : Akt at the converging crossroad?CDK inhibitor p57 (Kip2) is downregulated by Akt during HER2-mediated tumorigenicity.Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.Diversity of COP9 signalosome structures and functional consequences.From photomorphogenesis to cancer: a CSN journey.Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis.Mutations in the PCNA-binding site of CDKN1C inhibit cell proliferation by impairing the entry into S phase.Downregulation of CSN6 attenuates papillary thyroid carcinoma progression by reducing Wnt/β-catenin signaling and sensitizes cancer cells to FH535 therapy.COP9 signalosome subunit CSN5, but not CSN6, is upregulated in lung adenocarcinoma and predicts poor prognosis.

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P2860

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

http://www.wikidata.org/entity/Q36581691

description

2012 nî lūn-bûn

@nan

2012年の論文

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2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@ast

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@en

type

label

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@ast

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@en

prefLabel

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@ast

CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@en

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CDK inhibitor p57 (Kip2) is negatively regulated by COP9 signalosome subunit 6

@en

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Bo Chen

http://www.w3.org/2001/XMLSchema#string

Chieh Tseng

http://www.w3.org/2001/XMLSchema#string

Chun-Hui Su

http://www.w3.org/2001/XMLSchema#string

Feng Jin

http://www.w3.org/2001/XMLSchema#string

Heng-Yin Yang

http://www.w3.org/2001/XMLSchema#string

Huiling Yang

http://www.w3.org/2001/XMLSchema#string

Lekuan Fang

http://www.w3.org/2001/XMLSchema#string

Liem Phan

http://www.w3.org/2001/XMLSchema#string

Mong-Hong Lee

http://www.w3.org/2001/XMLSchema#string

Monica Linan

http://www.w3.org/2001/XMLSchema#string

P2860

MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function

Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression

COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation

Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

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4633-4641

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scholarly article

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10.4161/CC.22887

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24

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11

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2012-11-27T00:00:00Z

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233788610

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23187808

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3562308

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