The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
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Developmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular OriginTherapeutic potential of targeting acinar cell reprogramming in pancreatic cancerRegulation of Cellular Identity in CancerLGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1Connectivity of vertebrate genomes: Paired-related homeobox (Prrx) genes in spotted gar, basal teleosts, and tetrapods.The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progressionIsolation, culture and genetic manipulation of mouse pancreatic ductal cells.Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cellsMiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1PRRX1 and PRRX2 distinctively participate in pituitary organogenesis and a cell-supply system.Mechanisms governing metastatic dormancy and reactivation.Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation.Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasiaEukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression LevelsPrrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization.ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.Paired related homoeobox 1, a new EMT inducer, is involved in metastasis and poor prognosis in colorectal cancer.β1 integrin is a crucial regulator of pancreatic β-cell expansion.Silencing of Prrx1b suppresses cellular proliferation, migration, invasion and epithelial-mesenchymal transition in triple-negative breast cancer.Clinicopathologic Correlations of E-cadherin and Prrx-1 Expression Loss in Hepatocellular CarcinomaTriggering ubiquitination of IFNAR1 protects tissues from inflammatory injury.Transcriptional control of mammalian pancreas organogenesis.Alternative splicing of DNA damage response genes and gastrointestinal cancers.Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.The role of PRRX1 in the apoptosis of A549 cells induced by cisplatin.Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells.ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer.Pancreatic fibroblasts smoothen their activities via AKT-GLI2-TGFα.Phosphorylation of carboxypeptidase B1 protein regulates β-cell proliferation.Metadherin promotes metastasis by supporting putative cancer stem cell properties and epithelial plasticity in pancreatic cancer.Three-dimensional studies of Prop1-expressing cells in the rat pituitary just before birth.Metaplasia: tissue injury adaptation and a precursor to the dysplasia-cancer sequence.Paired related homeobox 1 transactivates dopamine D2 receptor to maintain propagation and tumorigenicity of glioma-initiating cells.Paired related homeobox protein 1 regulates PDGF-induced chemotaxis of hepatic stellate cells in liver fibrosis.ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.PRRX1 promotes epithelial-mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer.Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.
P2860
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P2860
The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@ast
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@en
type
label
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@ast
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@en
prefLabel
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@ast
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@en
P2093
P2860
P356
P1433
P1476
The Prrx1 homeodomain transcri ...... generation and carcinogenesis.
@en
P2093
Andrew D Rhim
Anil K Rustgi
Ben Z Stanger
Christopher Hahn
Günter Schneider
Johannes von Burstin
Ju-Seog Lee
Kaori Ihida-Stansbury
Maximilian Reichert
Sang-Bae Kim
P2860
P304
P356
10.1101/GAD.204453.112
P577
2013-01-25T00:00:00Z