Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry
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Inside out: the role of nucleocytoplasmic transport in ALS and FTLDTargeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal TransitionA deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the NucleolusBioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72.MetaMass, a tool for meta-analysis of subcellular proteomics data.The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturationComparative ultrastructure of CRM1-Nucleolar bodies (CNoBs), Intranucleolar bodies (INBs) and hybrid PML/p62 bodies uncovers new facets of nuclear body dynamic and diversityFoxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.NESmapper: accurate prediction of leucine-rich nuclear export signals using activity-based profiles.Cellular localization of CIP2A determines its prognostic impact in superficial spreading and nodular melanoma.Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compoundsTDP-43 and FUS en route from the nucleus to the cytoplasm.Preclinical activity of selinexor, an inhibitor of XPO1, in sarcomaIdentification of cargo proteins specific for importin-β with importin-α applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system.Zebrafish cytosolic carboxypeptidases 1 and 5 are essential for embryonic development.Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors.Extensive cargo identification reveals distinct biological roles of the 12 importin pathways.Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.Biological significance of the importin-β family-dependent nucleocytoplasmic transport pathways.The nuclear export factor CRM1 controls juxta-nuclear microtubule-dependent virus transport.CRM1 is a cellular target of curcumin: new insights for the myriad of biological effects of an ancient spice.Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation.Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.Providing activation-induced cytidine deaminase (AID) to nuclear export inhibitors. Response to: "Complex downstream effects of nuclear export inhibition in B-cell lymphomas: a possible role for activation-induced cytidine deaminase".The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini.Landscape of nuclear transport receptor cargo specificity.Protein phosphatases at the nuclear envelope.Extensive identification and in-depth validation of importin 13 cargoes.Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia.Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan.Xpo7 is a broad-spectrum exportin and a nuclear import receptor.
P2860
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P2860
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@ast
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@en
type
label
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@ast
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@en
prefLabel
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@ast
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@en
P2093
P2860
P356
P1476
Identification of CRM1-depende ...... Quantitative Mass Spectrometry
@en
P2093
Henning Urlaub
Ketan Thakar
Samir Karaca
P2860
P304
P356
10.1074/MCP.M112.024877
P577
2012-12-13T00:00:00Z