Hydrophobic CDR3 residues promote the development of self-reactive T cells.
about
Low-affinity CD4+ T cells are major responders in the primary immune responseInsights into immune system development and function from mouse T-cell repertoires.Characterization of T and B cell repertoire diversity in patients with RAG deficiencyAntigen-specific regulatory T-cell responses to intestinal microbiota.Restoring Regulatory T Cells in Type 1 Diabetes.A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.Abnormalities of T cell receptor repertoire in CD4(+) regulatory and conventional T cells in patients with RAG mutations: implications for autoimmunity.Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren's syndrome miceThe somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.A study of CDR3 loop dynamics reveals distinct mechanisms of peptide recognition by T-cell receptors exhibiting different levels of cross-reactivity.Patients with CD3G mutations reveal a role for human CD3γ in Treg diversity and suppressive function.HLA variation and disease.
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Hydrophobic CDR3 residues promote the development of self-reactive T cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 June 2016
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@en
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@nl
type
label
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@en
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@nl
prefLabel
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@en
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@nl
P2093
P2860
P50
P356
P1433
P1476
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
@en
P2093
Arup K Chakraborty
Brian D Stadinski
Eric S Huseby
Iria Gómez-Touriño
Karthik Shekhar
Katsuhiro Sasaki
P2860
P304
P356
10.1038/NI.3491
P407
P577
2016-06-27T00:00:00Z