Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk
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Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphateEvidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunctionEssential biphasic role for JAK3 catalytic activity in IL-2 receptor signalingThe accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).Itk derived signals regulate the expression of Th-POK and controls the development of CD4 T cells.IL-2-inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells.Sodium and potassium regulate endothelial phospholipase C-γ and Bmx.A genome-wide siRNA screen identifies novel phospho-enzymes affecting Wnt/β-catenin signaling in mouse embryonic stem cells.T-cell signaling regulated by the Tec family kinase, Itk.Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.Alternative memory in the CD8 T cell lineageThe CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.Lipid signaling in T-cell development and functionNeoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein.Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach.T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cellsKLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells.CD122+CD8+ Treg suppress vaccine-induced antitumor immune responses in lymphodepleted mice.Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.Gene-expression signatures: biomarkers toward diagnosing multiple sclerosisA molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitorsA unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice.Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation.T cell Receptor Signal Transduction in T lymphocytes.TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.NFAT2 Regulates Generation of Innate-Like CD8+ T Lymphocytes and CD8+ T Lymphocytes Responses.Proteasome inactivation promotes p38 mitogen-activated protein kinase-dependent phosphatidylinositol 3-kinase activation and increases interleukin-8 production in retinal pigment epithelial cells.CD4 and CD8: an inside-out coreceptor model for innate immune cells.Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases.Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT.ITK inhibitors in inflammation and immune-mediated disorders.Signaling pathways critical for allergic airway inflammation.SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions.The LAT story: a tale of cooperativity, coordination, and choreography.Tec family kinases: regulation of FcεRI-mediated mast-cell activation.Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells.TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.
P2860
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P2860
Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Tec kinases regulate T-lymphoc ...... o the roles of Itk and Rlk/Txk
@en
Tec kinases regulate T-lymphoc ...... the roles of Itk and Rlk/Txk.
@nl
type
label
Tec kinases regulate T-lymphoc ...... o the roles of Itk and Rlk/Txk
@en
Tec kinases regulate T-lymphoc ...... the roles of Itk and Rlk/Txk.
@nl
prefLabel
Tec kinases regulate T-lymphoc ...... o the roles of Itk and Rlk/Txk
@en
Tec kinases regulate T-lymphoc ...... the roles of Itk and Rlk/Txk.
@nl
P2093
P2860
P1476
Tec kinases regulate T-lymphoc ...... o the roles of Itk and Rlk/Txk
@en
P2093
Ana M Venegas
Julie A Readinger
Kristen L Mueller
Pamela L Schwartzberg
Reiko Horai
P2860
P304
P356
10.1111/J.1600-065X.2008.00757.X
P577
2009-03-01T00:00:00Z