Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T-cell activation by interfering with proximal T-cell-receptor signaling.
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Acceptor Substrate Discrimination in Phosphatidyl-myo-inositol Mannoside Synthesis: STRUCTURAL AND MUTATIONAL ANALYSIS OF MANNOSYLTRANSFERASE CORYNEBACTERIUM GLUTAMICUM PimB'Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteriaMycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cellsSuboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo.Mycobacterial antibody levels and immune restoration disease in HIV patients treated in South East Asia.Networked T cell death following macrophage infection by Mycobacterium tuberculosis.Manipulation of costimulatory molecules by intracellular pathogens: veni, vidi, vici!!Mycobacterium tuberculosis lipoproteins directly regulate human memory CD4(+) T cell activation via Toll-like receptors 1 and 2.Mycobacterial glycolipids di-O-acylated trehalose and tri-O-acylated trehalose downregulate inducible nitric oxide synthase and nitric oxide production in macrophages.Mycobacterium tuberculosis secretory proteins downregulate T cell activation by interfering with proximal and downstream T cell signalling eventsBacterial Membrane Vesicles Mediate the Release of Mycobacterium tuberculosis Lipoglycans and Lipoproteins from Infected Macrophages.Mycobacterium tuberculosis ManLAM inhibits T-cell-receptor signaling by interference with ZAP-70, Lck and LAT phosphorylation.Phenolic-glycolipid-1 and lipoarabinomannan preferentially modulate TCR- and CD28-triggered proximal biochemical events, leading to T-cell unresponsiveness in mycobacterial diseases.Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAILMannose-capped lipoarabinomannan from Mycobacterium tuberculosis preferentially inhibits sphingosine-1-phosphate-induced migration of Th1 cells.Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets.Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.Highly purified mycobacterial phosphatidylinositol mannosides drive cell-mediated responses and activate NKT cells in cattle.Mycobacterium tuberculosis Membrane Vesicles Inhibit T Cell Activation.Lipoarabinomannan-specific TNF-α and IFN-γ as markers of protective immunity against tuberculosis: a cohort study in an endemic setting.Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces soluble tumor necrosis factor receptor production through tumor necrosis factor alpha-converting enzyme activationGenetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection.Local and Systemic CD4+ T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis.Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan.
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P2860
Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T-cell activation by interfering with proximal T-cell-receptor signaling.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
@en
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
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type
label
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
@en
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
@nl
prefLabel
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
@en
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
@nl
P2093
P2860
P356
P1476
Mycobacterium tuberculosis cel ...... mal T-cell-receptor signaling.
@en
P2093
Clifford V Harding
Jennifer L Franko
Robert N Mahon
Roxana E Rojas
Scott A Fulton
W Henry Boom
P2860
P304
P356
10.1128/IAI.00222-09
P407
P577
2009-08-03T00:00:00Z