Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.
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Lnc-SGK1 induced by Helicobacter pylori infection and highsalt diet promote Th2 and Th17 differentiation in human gastric cancer by SGK1/Jun B signalingLoss of malin, but not laforin, results in compromised autophagic flux and proteasomal dysfunction in cells exposed to heat shock.SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in a mouse model for Lafora disease.Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux.SGK1 (glucose transport), dishevelled2 (wnt signaling), LC3/p62 (autophagy) and p53 (apoptosis) proteins are unaltered in Lafora disease.
P2860
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Activation of serum/glucocorti ...... agy defects in Lafora disease.
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Activation of serum/glucocorti ...... agy defects in Lafora disease.
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Activation of serum/glucocorti ...... agy defects in Lafora disease.
@en
Activation of serum/glucocorti ...... agy defects in Lafora disease.
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Activation of serum/glucocorti ...... agy defects in Lafora disease.
@en
Activation of serum/glucocorti ...... agy defects in Lafora disease.
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P2093
P2860
P356
P1476
Activation of serum/glucocorti ...... agy defects in Lafora disease.
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P2093
Pankaj Kumar Singh
Subramaniam Ganesh
Sweta Singh
P2860
P304
P356
10.1091/MBC.E13-05-0261
P577
2013-10-16T00:00:00Z