The H19 differentially methylated region marks the parental origin of a heterologous locus without gametic DNA methylation.
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Imprinted DNA methylation reconstituted at a non-imprinted locus.H19 imprinting control region methylation requires an imprinted environment only in the male germ line.Complete biallelic insulation at the H19/Igf2 imprinting control region position results in fetal growth retardation and perinatal lethalityFunctional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control regionGenomic imprinting recapitulated in the human beta-globin locus.Sequences sufficient for programming imprinted germline DNA methylation defined.Developmental profile of H19 differentially methylated domain (DMD) deletion alleles reveals multiple roles of the DMD in regulating allelic expression and DNA methylation at the imprinted H19/Igf2 locus.Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment.Insertion of an imprinted insulator into the IgH locus reveals developmentally regulated, transcription-dependent control of V(D)J recombination.The chicken HS4 insulator element does not protect the H19 ICR from differential DNA methylation in yeast artificial chromosome transgenic mouseAccurate quantitation of allele-specific expression patterns by analysis of DNA melting.Analysis of the H19ICR insulatorGenomic imprinting: recognition and marking of imprinted loci.Epigenetic mechanisms of genomic imprinting: common themes in the regulation of imprinted regions in mammals, plants, and insects.More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain.Promoter cross-talk via a shared enhancer explains paternally biased expression of Nctc1 at the Igf2/H19/Nctc1 imprinted locus.The H19 imprinting control region mediates preimplantation imprinted methylation of nearby sequences in yeast artificial chromosome transgenic mice.A randomly integrated transgenic H19 imprinting control region acquires methylation imprinting independently of its establishment in germ cells.Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo.Genetic and epigenetic dysregulation of imprinted genes in the brain.The transcriptional status but not the imprinting control region determines allele-specific histone modifications at the imprinted H19 locus.H19ICR mediated transcriptional silencing does not require target promoter methylation.
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The H19 differentially methylated region marks the parental origin of a heterologous locus without gametic DNA methylation.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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The H19 differentially methyla ...... thout gametic DNA methylation.
@en
The H19 differentially methyla ...... thout gametic DNA methylation.
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The H19 differentially methyla ...... thout gametic DNA methylation.
@en
The H19 differentially methyla ...... thout gametic DNA methylation.
@nl
prefLabel
The H19 differentially methyla ...... thout gametic DNA methylation.
@en
The H19 differentially methyla ...... thout gametic DNA methylation.
@nl
P2093
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P1476
The H19 differentially methyla ...... thout gametic DNA methylation.
@en
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Alexander Grinberg
Elizabeth A Sellars
Karl Pfeifer
Kye-Yoon Park
Sing-Ping Huang
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P304
P356
10.1128/MCB.24.9.3588-3595.2004
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P577
2004-05-01T00:00:00Z