Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection.
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A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cellsSusceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with PeptideEnthalpy-entropy compensation and cooperativity as thermodynamic epiphenomena of structural flexibility in ligand-receptor interactionsFor many but not for all: how the conformational flexibility of the peptide/MHCII complex shapes epitope selectionStructural and dynamical insights on HLA-DR2 complexes that confer susceptibility to multiple sclerosis in Sardinia: a molecular dynamics simulation studyDifferential transmembrane domain GXXXG motif pairing impacts major histocompatibility complex (MHC) class II structure.HLA-DO and Its Role in MHC Class II Antigen Presentation.HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange.Cohesin regulates MHC class II genes through interactions with MHC class II insulators.Single-chain recombinant HLA-DQ2.5/peptide molecules block α2-gliadin-specific pathogenic CD4+ T-cell proliferation and attenuate production of inflammatory cytokines: a potential therapy for celiac disease.A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing.Antigenic peptide molecular recognition by the DRB1-DQB1 haplotype modulates multiple sclerosis susceptibility.Immune regulation by intralymphatic immunotherapy with modular allergen translocation MAT vaccine.Analysis of peptide-SLA binding by establishing immortalized porcine alveolar macrophage cells with different SLA class II haplotypes
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Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on July 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Conformational heterogeneity o ...... ntation and epitope selection.
@en
Conformational heterogeneity o ...... ntation and epitope selection.
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type
label
Conformational heterogeneity o ...... ntation and epitope selection.
@en
Conformational heterogeneity o ...... ntation and epitope selection.
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prefLabel
Conformational heterogeneity o ...... ntation and epitope selection.
@en
Conformational heterogeneity o ...... ntation and epitope selection.
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P2093
P2860
P1433
P1476
Conformational heterogeneity o ...... ntation and epitope selection.
@en
P2093
AeRyon Kim
Chih-Ling Chou
Isamu Z Hartman
Kedar Narayan
Sateesh Natarajan
Scheherazade Sadegh-Nasseri
P2860
P2888
P356
10.1007/S12026-009-8138-1
P577
2010-07-01T00:00:00Z