PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas. - sprookjes - yvandenbroek - TriplyDB

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

http://www.wikidata.org/entity/Q37716625

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PLK1 inhibitor facilitates the suppressing effect of temozolomide on human brain glioma stem cells

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PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

http://www.wikidata.org/entity/Q37716625

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article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 02 February 2017

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

@en

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

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type

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PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

@en

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

@nl

prefLabel

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

@en

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

@nl

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ONCOTARGET.15015

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PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas.

@en

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El Mustapha Bahassi

http://www.w3.org/2001/XMLSchema#string

Robert F Koncar

http://www.w3.org/2001/XMLSchema#string

Susanne I Wells

http://www.w3.org/2001/XMLSchema#string

Timothy A Chan

http://www.w3.org/2001/XMLSchema#string

Xiaoyang Qi

http://www.w3.org/2001/XMLSchema#string

Zhengtao Chu

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

IDH1 and IDH2 mutations in gliomas

The 2007 WHO classification of tumours of the central nervous system

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery

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15827-15837

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scholarly article

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10.18632/ONCOTARGET.15015

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9

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8

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Lindsey E Romick-Rosendale

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2017-02-02T00:00:00Z

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28178660

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5362526

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