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Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profilingCharacterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodiesA Phase II study of Dovitinib in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma.NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Mutation signature of adenoid cystic carcinoma: evidence for transcriptional and epigenetic reprogrammingOmics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa.A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma.MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.Adenoid cystic carcinoma of breast: Recent advances.Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosisFatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significance.Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma.A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets.Hematopoietic stem cell quiescence and function are controlled by the CYLD-TRAF2-p38MAPK pathway.The role of Notch receptors in transcriptional regulationNotch-1 knockdown suppresses proliferation, migration and metastasis of salivary adenoid cystic carcinoma cells.High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy.MYB rearrangement and clinicopathologic characteristics in head and neck adenoid cystic carcinoma.Molecular genetic studies on EGFR, KRAS, BRAF, ALK, PIK3CA, PDGFRA, and DDR2 in primary pulmonary adenoid cystic carcinoma.Targeted next generation sequencing of parotid gland cancer uncovers genetic heterogeneity.Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing.Clinicopathological and Targeted Exome Gene Features of a Patient with Metastatic Acinic Cell Carcinoma of the Parotid Gland Harboring an ARID2 Nonsense Mutation and CDKN2A/B Deletion.Genomic landscape of adenoid cystic carcinoma of the breastNovel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) TranslocationsAdenoid cystic carcinoma of sublingual salivary gland obstructing the submandibular salivary gland duct.Intestinal-specific activatable Myb initiates colon tumorigenesis in mice.Overexpression of MYB drives proliferation of CYLD-defective cylindroma cellsA phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screeningPRL-3 promotes migration and invasion and is associated with poor prognosis in salivary adenoid cystic carcinoma.The impact of the MYB-NFIB fusion proto-oncogene in vivo.Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.Adenoid cystic carcinoma: emerging role of translocations and gene fusionsDown-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway.Genomic approaches for studying craniofacial disorders.Splicing factor mutations and cancer.Therapeutic modulation of Notch signalling--are we there yet?Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 June 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Whole exome sequencing of adenoid cystic carcinoma.
@en
Whole exome sequencing of adenoid cystic carcinoma.
@nl
type
label
Whole exome sequencing of adenoid cystic carcinoma.
@en
Whole exome sequencing of adenoid cystic carcinoma.
@nl
prefLabel
Whole exome sequencing of adenoid cystic carcinoma.
@en
Whole exome sequencing of adenoid cystic carcinoma.
@nl
P2093
P2860
P50
P356
P1476
Whole exome sequencing of adenoid cystic carcinoma.
@en
P2093
Adam P Butler
Adam Shlien
Adel K El-Naggar
Alagu Jayakumar
Angela Cheverton
Claire Hardy
David J McBride
David Jones
Graham R Bignell
Helen R Davies
P2860
P304
P356
10.1172/JCI67201
P407
P50
P577
2013-06-17T00:00:00Z