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Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of boneMutational processes molding the genomes of 21 breast cancersCombined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancersDeciphering signatures of mutational processes operative in human cancerMutational signatures of ionizing radiation in second malignanciesTracing the origin of disseminated tumor cells in breast cancer using single-cell sequencingMitochondrial genetic diversity, selection and recombination in a canine transmissible cancerLiquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion.A comparison of different chemometrics approaches for the robust classification of electronic nose data.ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data.Recurrent PTPRB and PLCG1 mutations in angiosarcoma.Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer.Landscape of somatic mutations in 560 breast cancer whole-genome sequences.Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancerAutomated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets.Spatial and temporal diversity in genomic instability processes defines lung cancer evolution.Differential and limited expression of mutant alleles in multiple myeloma.Transmissible [corrected] dog cancer genome reveals the origin and history of an ancient cell lineage.Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer.The evolutionary history of lethal metastatic prostate cancer.Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.Subclonal diversification of primary breast cancer revealed by multiregion sequencing.Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomesEffect of mutation order on myeloproliferative neoplasms.Clock-like mutational processes in human somatic cells.Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics.Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.Direct Transcriptional Consequences of Somatic Mutation in Breast CancerClinical and biological implications of driver mutations in myelodysplastic syndromes.Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.Whole exome sequencing of adenoid cystic carcinoma.Analysis of a complete DNA-protein affinity landscape.Aptamer evolution for array-based diagnostics.Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape.RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
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description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
David C Wedge
@nl
David C Wedge
@sl
David C. Wedge
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David C. Wedge
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type
label
David C Wedge
@nl
David C Wedge
@sl
David C. Wedge
@en
David C. Wedge
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altLabel
Wedge DC
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prefLabel
David C Wedge
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David C Wedge
@sl
David C. Wedge
@en
David C. Wedge
@es
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P1153
13205301200
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P2798
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P496
0000-0002-7572-3196