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Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerizationThe structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutantMDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.MDM2 oligomers: antagonizers of the guardian of the genome.Association between murine double minute 2 T309G polymorphism and risk of liver cancer.Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment.Bridged Analogues for p53-Dependent Cancer Therapy Obtained by S-AlkylationMolecular dynamic simulation insights into the normal state and restoration of p53 function.Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Inhibitors of MDM2 and MDMX: a structural perspective.
@en
Inhibitors of MDM2 and MDMX: a structural perspective.
@nl
type
label
Inhibitors of MDM2 and MDMX: a structural perspective.
@en
Inhibitors of MDM2 and MDMX: a structural perspective.
@nl
prefLabel
Inhibitors of MDM2 and MDMX: a structural perspective.
@en
Inhibitors of MDM2 and MDMX: a structural perspective.
@nl
P2860
P356
P1476
Inhibitors of MDM2 and MDMX: a structural perspective
@en
P2093
Christiane Riedinger
P2860
P304
P356
10.4155/FMC.09.75
P577
2009-09-01T00:00:00Z