Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development.
about
Cofactor-independent phosphoglycerate mutase from nematodes has limited druggability, as revealed by two high-throughput screensDiscovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and DockingAnalysis of the Resistance of Hepatitis C Virus NS5B Polymerase Inhibitors via Docking and Molecular Dynamics Simulation.Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase.New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors.Discovery of new scaffolds for rational design of HCV NS5B polymerase inhibitors.Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymeraseUse of allosteric targets in the discovery of safer drugs.Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitors.Maria Letizia Barreca on hepatitis C virus treatment and control.Computational medicinal chemistry: part III.
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P2860
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Allosteric inhibition of the h ...... rug discovery and development.
@en
Allosteric inhibition of the h ...... rug discovery and development.
@nl
type
label
Allosteric inhibition of the h ...... rug discovery and development.
@en
Allosteric inhibition of the h ...... rug discovery and development.
@nl
prefLabel
Allosteric inhibition of the h ...... rug discovery and development.
@en
Allosteric inhibition of the h ...... rug discovery and development.
@nl
P2860
P50
P356
P1476
Allosteric inhibition of the h ...... rug discovery and development.
@en
P2093
Nunzio Iraci
P2860
P304
P356
10.4155/FMC.11.53
P577
2011-06-01T00:00:00Z