about
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitorPyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors.New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors.Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.Accounting for target flexibility and water molecules by docking to ensembles of target structures: the HCV NS5B palm site I inhibitors case study.Ethyl 1,8-naphthyridone-3-carboxylates downregulate human papillomavirus-16 E6 and E7 oncogene expression.The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development.A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors.Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold.Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors.Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase.Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity.Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives.Structure modifications of 6-aminoquinolones with potent anti-HIV activity.A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits.Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly.Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor.Synthesis and anti-BVDV activity of acridones as new potential antiviral agents.Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition.Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium.Structure-activity relationship study on anti-HIV 6-desfluoroquinolones.Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers.A Comprehensive Structural Overview of p38α Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders.Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase.Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance.1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions.Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel openerStudies on anti-HIV quinolones: New insights on the C-6 positionDiscovery of Novel Inhibitors of the NorA Multidrug Transporter ofStaphylococcus aureus2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group IntroductionStudies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 positionEvolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of theS. aureusNorA Efflux PumpModifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment AdjuvantsC-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors
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description
hulumtues
@sq
researcher
@en
ricercatore
@it
wetenschapper
@nl
հետազոտող
@hy
name
Giuseppe Manfroni
@ast
Giuseppe Manfroni
@en
Giuseppe Manfroni
@es
Giuseppe Manfroni
@nl
Giuseppe Manfroni
@sl
type
label
Giuseppe Manfroni
@ast
Giuseppe Manfroni
@en
Giuseppe Manfroni
@es
Giuseppe Manfroni
@nl
Giuseppe Manfroni
@sl
prefLabel
Giuseppe Manfroni
@ast
Giuseppe Manfroni
@en
Giuseppe Manfroni
@es
Giuseppe Manfroni
@nl
Giuseppe Manfroni
@sl
P214
P106
P1153
6503848637
P21
P214
P31
P396
IT\ICCU\CFIV\258742
P496
0000-0003-0207-3927
P569
1975-01-01T00:00:00Z
P735
P7859
viaf-307339021