Winning the arms race by improving drug discovery against mutating targets.
about
Understanding the structural mechanisms of antibiotic resistance sets the platform for new discoveryStructure-based evaluation of non-nucleoside inhibitors with improved potency and solubility that target HIV reverse transcriptase variants.Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex.Pulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts.In search of a treatment for HIV--current therapies and the role of non-nucleoside reverse transcriptase inhibitors (NNRTIs).Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.Elucidating a relationship between conformational sampling and drug resistance in HIV-1 protease.
P2860
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P2860
Winning the arms race by improving drug discovery against mutating targets.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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name
Winning the arms race by improving drug discovery against mutating targets.
@en
Winning the arms race by improving drug discovery against mutating targets.
@nl
type
label
Winning the arms race by improving drug discovery against mutating targets.
@en
Winning the arms race by improving drug discovery against mutating targets.
@nl
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Winning the arms race by improving drug discovery against mutating targets.
@en
Winning the arms race by improving drug discovery against mutating targets.
@nl
P2860
P356
P1433
P1476
Winning the arms race by improving drug discovery against mutating targets.
@en
P2093
Amy C Anderson
P2860
P304
P356
10.1021/CB200394T
P577
2011-11-11T00:00:00Z